{"id":"W4235969444","doi":"10.1158/1538-7445.am2019-ct122","title":"Abstract CT122: Randomized assessment of cisplatin dose interval for ototoxicity in the treatment of locally advanced squamous cell carcinoma of the head and neck undergoing curative concurrent chemoradiotherapy (RADIO)","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Western University","funders":"","keywords":"Medicine; Ototoxicity; Cisplatin; Randomized controlled trial; Head and neck cancer; Radiation therapy; Oncology; Chemoradiotherapy; Mucositis; Head and neck squamous-cell carcinoma; Internal medicine; Cancer; Chemotherapy; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002040881,0.001661257,0.003846921,0.0004737777,0.00045565,0.001456234,0.0009332039,0.001882214,0.01832289],"category_scores_gemma":[0.005910962,0.000622273,0.00554068,0.0006772633,0.0008427259,0.001200833,0.0007953827,0.002848767,0.001470328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001392879,"about_ca_system_score_gemma":0.001401321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002173504,"about_ca_topic_score_gemma":0.004051047,"domain_scores_codex":[0.9984389,0.000890594,0.000201364,0.0002481863,0.0001287903,0.00009218544],"domain_scores_gemma":[0.9981053,0.0005709121,0.0006216018,0.0001540594,0.0002048488,0.0003432397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9718665,0.002354019,0.0005121649,0.004090122,0.006209271,0.0000349046,0.00003393896,0.0004428581,0.001031717,0.0001440197,0.0009801402,0.0123004],"study_design_scores_gemma":[0.9346002,0.05371069,0.00242332,0.0004116392,0.006597284,0.00003287698,0.00003181418,0.0005134416,0.0002674988,0.0003407584,0.001041178,0.00002923693],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9118057,0.03434142,0.002966525,0.003309892,0.004220589,0.02969834,0.00518876,0.0004203678,0.008048412],"genre_scores_gemma":[0.9711354,0.005001343,0.002325671,0.001724903,0.0006967045,0.01297644,0.001736568,0.00003702678,0.004366076],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01832289,"threshold_uncertainty_score":0.06129616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06144599019396137,"score_gpt":0.4278888982429266,"score_spread":0.3664429080489652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}