{"id":"W4236152653","doi":"10.1093/neuonc/noy148.863","title":"PDTM-21. MATCHING OF SINGLE CELL TRANSCRIPTOMICS FROM CEREBELLAR DEVELOPMENT IDENTIFIES PUTATIVE SUBGROUP SPECIFIC CELLS OF ORIGIN FOR MEDULLOBLASTOMA","year":2018,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Calgary; McGill University; Hospital for Sick Children; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Biology; Medulloblastoma; Population; Cerebellum; Lineage markers; Single-cell analysis; Progenitor cell; Stem cell; Genetics; Cell; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002902978,0.0003475611,0.0005246266,0.0004315186,0.0005941571,0.0007181752,0.0003999145,0.0004912433,0.003141325],"category_scores_gemma":[0.0004154649,0.0003441996,0.0004638773,0.0004402101,0.0002412114,0.0001750795,0.0005805386,0.0007615312,0.002099181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006470556,"about_ca_system_score_gemma":0.0006580951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002810423,"about_ca_topic_score_gemma":0.01047818,"domain_scores_codex":[0.9996369,0.00001680057,0.00002015198,0.0001583764,0.0001164235,0.00005136466],"domain_scores_gemma":[0.9998215,0.00003894145,0.00003870634,0.00003298621,0.0000328504,0.00003501862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001575501,0.00002060743,0.004687541,0.0001493492,0.00002330051,0.0001170456,0.00009874099,0.000594046,0.9829568,0.0003326314,0.001717865,0.009144495],"study_design_scores_gemma":[0.00006242793,0.0003332582,0.1075361,0.00005428055,0.0001354334,0.001082302,0.0001727123,0.01308831,0.7841442,0.0006955507,0.0926503,0.00004519903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8290625,0.002140639,0.04349906,0.0004436443,0.0001806315,0.0003384428,0.1070178,0.004845522,0.01247162],"genre_scores_gemma":[0.7433655,0.001252658,0.06718682,0.0006359981,0.00004534145,0.0009419094,0.1666036,0.002178667,0.0177896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003141325,"threshold_uncertainty_score":0.01050872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04131868790255169,"score_gpt":0.3141205460476487,"score_spread":0.2728018581450971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}