{"id":"W4236445904","doi":"10.1007/s40274-020-7285-4","title":"Non-invasive prenatal Down syndrome screening \"affordable\" in Canada","year":2020,"lang":"en","type":"article","venue":"PharmacoEconomics & Outcomes News","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Quality of Life Research; Medicine; Public health; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001044738,0.0003352828,0.0007473828,0.0000994048,0.00006276742,0.00004028884,0.0003088966,0.00006988821,0.0003559025],"category_scores_gemma":[0.0002583371,0.0003274973,0.0001524135,0.0001761593,0.0000285406,0.0002436498,0.000212796,0.0004935984,0.0001179747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005102681,"about_ca_system_score_gemma":0.001387008,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.6928813,"about_ca_topic_score_gemma":0.5192044,"domain_scores_codex":[0.9980824,0.00002538813,0.0006164873,0.000494706,0.0001906086,0.0005904221],"domain_scores_gemma":[0.9984122,0.0004094468,0.00016467,0.0002719207,0.00003203338,0.0007097218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000272386,0.00005232184,0.966688,0.000180468,0.0002204997,0.001454435,0.0002388491,0.003441604,0.0001890596,0.0000355526,0.02090899,0.006317805],"study_design_scores_gemma":[0.02656386,0.0006451951,0.8391694,0.0005711467,0.0006051856,0.0006862088,0.001840165,0.06577175,0.01841035,0.00008069529,0.04345005,0.002206025],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9726002,0.0002176746,0.000250642,0.02266494,0.0003761862,0.0006113637,0.0001792527,0.00007742114,0.003022275],"genre_scores_gemma":[0.9529469,0.0001260409,0.001691833,0.04474552,0.0001409791,0.0000356958,0.0001260582,0.00004978226,0.0001371704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1736769,"threshold_uncertainty_score":0.9999177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02141501198070292,"score_gpt":0.282073091242399,"score_spread":0.260658079261696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}