{"id":"W4236679755","doi":"10.1002/ange.201606006","title":"Total Biosynthesis of Legionaminic Acid, a Bacterial Sialic Acid Analogue","year":2016,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Joint Attosecond Science Laboratory; University of Ottawa","funders":"National Research Council Canada; Natural Sciences and Engineering Research Council of Canada; University of Ottawa","keywords":"Glycobiology; Campylobacter jejuni; Legionella pneumophila; Microbiology; Biochemistry; Sialic acid; Escherichia coli; Biology; Biosynthesis; Bacteria; Bacterial cell structure; Neuraminic acid; Glycoconjugate; Virulence; Glycan; Chemistry; Enzyme; Glycoprotein; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001339163,0.0004785006,0.0002383069,0.0001956353,0.0001336101,0.0003660889,0.0001803997,0.0001953352,0.0004788493],"category_scores_gemma":[0.0001140417,0.0001189673,0.0002104857,0.0003093306,0.0001527165,0.0002333569,0.000358646,0.0002861627,0.0002747694],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004458,"about_ca_system_score_gemma":0.0003824149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009563058,"about_ca_topic_score_gemma":0.001838882,"domain_scores_codex":[0.9998778,0.0000238712,0.00001047805,0.00002551102,0.00003353849,0.00002878708],"domain_scores_gemma":[0.9999242,0.000005562982,0.00001527228,0.00001477681,0.00001386494,0.00002644002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000593814,0.00001384606,0.0001642164,0.00004488841,0.000009463232,0.00004498702,0.00001175627,0.0001664453,0.9974662,0.0001910282,0.00002815554,0.001799622],"study_design_scores_gemma":[0.000007173796,0.0001314133,0.0006047185,0.000006112442,0.00001466721,0.00007309886,0.00001289682,0.0004617486,0.9952792,0.00005944136,0.003344339,0.000005259716],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819564,0.001449815,0.011879,0.00006836956,0.00003900316,0.00004420928,0.0008714493,0.0001600523,0.003531713],"genre_scores_gemma":[0.9853653,0.0009708655,0.009729305,0.00002462626,0.0000039023,0.00002368406,0.0009974021,0.00002926754,0.002855552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009563058,"threshold_uncertainty_score":0.003234506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01729875171413089,"score_gpt":0.2535148942561471,"score_spread":0.2362161425420163,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}