{"id":"W4237151352","doi":"10.21203/rs.2.276/v1","title":"Tranexamic acid for acute gastrointestinal bleeding (The HALT-IT trial): Statistical analysis plan for an international, randomised, double blind, placebo-controlled trial","year":2019,"lang":"en","type":"preprint","venue":"Research Square","topic":"Gastrointestinal Bleeding Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Health Technology Assessment Programme; National Institute for Health and Care Research","keywords":"Tranexamic acid; Medicine; Placebo; Upper gastrointestinal bleeding; Randomized controlled trial; Gastrointestinal bleeding; Surgery; Internal medicine; Anesthesia; Endoscopy; Blood loss","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04858847,0.0044619,0.01077792,0.001914858,0.000914524,0.003053073,0.002131337,0.004470249,0.03171821],"category_scores_gemma":[0.06101702,0.001303471,0.0127724,0.002411338,0.002237504,0.003115939,0.001877772,0.006302656,0.003515051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002402975,"about_ca_system_score_gemma":0.004286708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001083368,"about_ca_topic_score_gemma":0.001236586,"domain_scores_codex":[0.9390025,0.05086938,0.002938653,0.002595159,0.00281269,0.001781629],"domain_scores_gemma":[0.97921,0.0100378,0.004649958,0.002243252,0.002686053,0.001172932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9343449,0.0005887881,0.001123525,0.01634826,0.01205703,0.00007547541,0.00009897601,0.001726154,0.0006950109,0.00322954,0.01114749,0.01856477],"study_design_scores_gemma":[0.93442,0.01433446,0.003005424,0.004184098,0.01565124,0.00006115231,0.00009948782,0.007425646,0.0008429013,0.006409856,0.01345055,0.0001151445],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.04773272,0.01816416,0.04889332,0.005216426,0.007316251,0.8344059,0.02420812,0.0019192,0.01214392],"genre_scores_gemma":[0.05302926,0.001975065,0.03736382,0.002248778,0.0005659051,0.8979471,0.003296779,0.0001595481,0.003413617],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04858847,"threshold_uncertainty_score":0.2569634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1632865670567673,"score_gpt":0.4612887355283857,"score_spread":0.2980021684716184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}