{"id":"W4237479443","doi":"10.24820/ark.5550190.p009.905","title":"Synthesis and biological evaluation of (E)-cinnamic acid, (E)-2-styrylthiazole and (E)-2-[2-(naphthalen-1-yl)vinyl]thiazole derivatives","year":2017,"lang":"en","type":"article","venue":"ARKIVOC","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Centre","funders":"Department of Science and Technology, Ministry of Science and Technology, India; Medical Research Council; Rhodes University; South African Medical Research Council; National Research Foundation","keywords":"Chemistry; Thiazole; Organic chemistry; Cinnamic acid; Medicinal chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009570719,0.0002393061,0.0004235446,0.0000387442,0.0003902077,0.00007986997,0.000308396,0.0002841922,0.0006562692],"category_scores_gemma":[0.002316194,0.0001684361,0.00008249943,0.00003420506,0.0006866277,0.0002062262,0.0002987812,0.0001728357,0.000007418348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002877613,"about_ca_system_score_gemma":0.00003098212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007613417,"about_ca_topic_score_gemma":0.00001964651,"domain_scores_codex":[0.9985036,0.0001308984,0.0002967868,0.0004970837,0.0002964556,0.0002751751],"domain_scores_gemma":[0.9983653,0.0004972451,0.0003594245,0.000541658,0.0001280226,0.0001083915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009536914,0.0001820355,0.1934083,0.00007847101,0.00008653197,0.00000328681,0.0001235969,6.383402e-7,0.62311,0.0003764526,0.00003405363,0.1825012],"study_design_scores_gemma":[0.0004672604,0.00005429836,0.4114519,0.0001018685,0.00008388513,0.00001927487,0.0002655216,0.0008087775,0.5837284,0.002364384,0.0003896051,0.0002648051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864113,0.001029793,0.00001700667,0.0004515998,0.00004121413,0.0001125875,0.00004868418,0.0000396947,0.01184815],"genre_scores_gemma":[0.9988977,0.0005555041,0.0003158736,0.00003394713,0.00008338685,0.00004844397,0.000005815501,0.00001223269,0.00004711135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2180436,"threshold_uncertainty_score":0.7185687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08140342775000724,"score_gpt":0.3057043024329733,"score_spread":0.224300874682966,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}