{"id":"W4237947375","doi":"10.1554/0014-3820(2000)054[1654:fatgli]2.0.co;2","title":"FACTORS AFFECTING THE GENETIC LOAD IN DROSOPHILA: SYNERGISTIC EPISTASIS AND CORRELATIONS AMONG FITNESS COMPONENTS","year":2000,"lang":"en","type":"article","venue":"Evolution","topic":"Evolution and Genetic Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Epistasis; Genetic load; Mating; Genetics; Genetic Fitness; Drosophila melanogaster; Population; Fixation (population genetics); Fecundity; Reproductive success; Allele; Productivity; Evolutionary biology; Gene; Demography; Inbreeding","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004110734,0.000474749,0.0005774342,0.0006358433,0.0002237961,0.0005175839,0.0002039558,0.0002832683,0.0005943366],"category_scores_gemma":[0.001550824,0.0002382728,0.0002663176,0.0004299349,0.0002609369,0.0003831944,0.0004050725,0.0002674504,0.00006947717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003613833,"about_ca_system_score_gemma":0.0002279909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007610458,"about_ca_topic_score_gemma":0.001747983,"domain_scores_codex":[0.9996614,0.00008438181,0.00002850083,0.00007548732,0.0001193236,0.00003089579],"domain_scores_gemma":[0.9992123,0.0003276068,0.0002313995,0.00004850027,0.00008286761,0.00009725271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007845595,0.0001374986,0.1086458,0.0003260773,0.0002669719,0.0007135067,0.0001456636,0.004710407,0.8299687,0.001275762,0.0002934217,0.05273164],"study_design_scores_gemma":[0.00008277936,0.0006825476,0.8955144,0.00002213663,0.0002935724,0.002125175,0.0001505788,0.02948618,0.06747735,0.002714103,0.001367994,0.00008313378],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974831,0.0002832474,0.001750605,0.00005764472,0.000002811468,0.000006864198,0.00006767211,0.0000165072,0.0003316225],"genre_scores_gemma":[0.9974088,0.0003071078,0.001787794,0.00003315745,0.0000122799,0.00001137992,0.0001121956,0.00001158695,0.0003156798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007610458,"threshold_uncertainty_score":0.002622008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01061644076186817,"score_gpt":0.2299183971599252,"score_spread":0.219301956398057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}