{"id":"W4238230577","doi":"10.1016/j.cjca.2015.07.249","title":"THE ROLE OF ENDOPLASMIC RETICULUM STRESS AND GLYCOGEN SYNTHASE KINASE-3α/β IN ATHEROSCLEROTIC PROGRESSION AND REGRESSION","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Endocrinology; Internal medicine; Endoplasmic reticulum; GSK-3; Unfolded protein response; LDL receptor; Glycogen synthase; Glycogen; GSK3B; Cholesterol; Fatty acid synthase; Kinase; Lipoprotein; Lipid metabolism; Biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005329992,0.0003729684,0.0003969801,0.000549999,0.0003945218,0.0008082184,0.0002940337,0.0003607592,0.0008619414],"category_scores_gemma":[0.0004006996,0.0002329264,0.0002740653,0.0003323098,0.0005610246,0.0003192599,0.0003191111,0.0007241943,0.0002182745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001129666,"about_ca_system_score_gemma":0.001818759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01408365,"about_ca_topic_score_gemma":0.01716371,"domain_scores_codex":[0.9997945,0.00003459681,0.00001311802,0.0000233069,0.00005708196,0.00007735617],"domain_scores_gemma":[0.9997548,0.00001899796,0.00005822092,0.0000202616,0.00006380868,0.00008385957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01943262,0.0012251,0.06931908,0.001011119,0.0005658178,0.004268456,0.0007071786,0.001603907,0.6567006,0.01661196,0.006306627,0.2222476],"study_design_scores_gemma":[0.0006494501,0.001880142,0.8783973,0.0002066005,0.000391303,0.002720247,0.001240272,0.002769799,0.07019243,0.008759716,0.0326946,0.00009825026],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8083791,0.1644468,0.003164145,0.004583984,0.0005447919,0.00008830748,0.0003594343,0.0001332638,0.01830027],"genre_scores_gemma":[0.968417,0.02334877,0.001034271,0.0002977658,0.0001618468,0.00002923446,0.000146338,0.00001437032,0.006550412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01408365,"threshold_uncertainty_score":0.02800333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00755245358189478,"score_gpt":0.2296267612230654,"score_spread":0.2220743076411706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}