{"id":"W4238323606","doi":"10.1083/jcb.2112oia232","title":"TLR9 ligation in pancreatic stellate cells promotes tumorigenesis","year":2015,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Cancer Institute; Deutsche Forschungsgemeinschaft; York University; NYU Langone Medical Center; Pancreatic Cancer Action Network; U.S. Department of Defense","keywords":"Biology; Hepatic stellate cell; Ligation; Carcinogenesis; Cell biology; TLR9; Pancreas; Cancer research; Molecular biology; Genetics; Endocrinology; Cancer; DNA methylation; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003212031,0.0004715727,0.0004324251,0.0004698098,0.0003709136,0.0007945763,0.0001740954,0.0004953433,0.005725573],"category_scores_gemma":[0.0001699312,0.0003136673,0.0005819665,0.0002786647,0.0004592135,0.0003953676,0.0004730539,0.001944597,0.001878476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002891156,"about_ca_system_score_gemma":0.0004038714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003695155,"about_ca_topic_score_gemma":0.0007772404,"domain_scores_codex":[0.9995543,0.0001129487,0.00005381586,0.00006547313,0.00007566107,0.0001377586],"domain_scores_gemma":[0.9997298,0.00004277085,0.00004818078,0.00004112479,0.00001429873,0.0001238883],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002134759,0.0002867732,0.000799686,0.0001297755,0.00001874588,0.0002888984,0.00005765446,0.0001723102,0.9917625,0.0003998339,0.0006777937,0.00327122],"study_design_scores_gemma":[0.0001258009,0.00121267,0.006104461,0.0000192498,0.0000439025,0.0004698007,0.0002789118,0.001176171,0.9831204,0.000194029,0.00724262,0.00001183938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904281,0.001420883,0.001773639,0.0008988794,0.0003367864,0.00003395853,0.0009140457,0.0003160007,0.003877725],"genre_scores_gemma":[0.9929489,0.000714604,0.0007798948,0.0001620993,0.00004374705,0.00004366877,0.0005964926,0.00002406683,0.00468647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005725573,"threshold_uncertainty_score":0.01915389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04796919465432518,"score_gpt":0.333774043043673,"score_spread":0.2858048483893478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}