{"id":"W4238349297","doi":"10.1002/9781118981559.ch25","title":"Prenatal Diagnosis of Miscellaneous Biochemical Disorders","year":2015,"lang":"en","type":"other","venue":"","topic":"Biomedical Research and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Cystinosis; Methylenetetrahydrofolate reductase; Homocystinuria; Prenatal diagnosis; Medicine; Maple syrup urine disease; Malabsorption; Pregnancy; Biology; Genetics; Internal medicine; Methionine; Biochemistry; Cystine; Gene; Fetus; Enzyme; Allele","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002790345,0.0005015552,0.0002957388,0.001414371,0.0005658881,0.0004704359,0.0002996429,0.000724992,0.01373193],"category_scores_gemma":[0.002160305,0.000188439,0.0002551273,0.0004118591,0.0003083434,0.000385657,0.0005289027,0.0006797386,0.002021197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004164947,"about_ca_system_score_gemma":0.0005701975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002051232,"about_ca_topic_score_gemma":0.002585102,"domain_scores_codex":[0.9996817,0.0000587195,0.00003117778,0.00004079124,0.0001344904,0.00005306778],"domain_scores_gemma":[0.9996541,0.0001772171,0.00005637911,0.00001633433,0.00005672373,0.00003927392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002197093,0.00008748557,0.0338412,0.001048484,0.0000487701,0.09365106,0.001292002,0.0004545002,0.009645616,0.01803644,0.07428581,0.7673889],"study_design_scores_gemma":[0.00002180473,0.0001014343,0.02104931,0.002404857,0.00009415814,0.4850805,0.0008026916,0.0004220475,0.01161541,0.007469337,0.4709001,0.00003830794],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.1608734,0.3681308,0.04279888,0.03233183,0.00499723,0.0003086044,0.003611435,0.002006675,0.3849412],"genre_scores_gemma":[0.5285556,0.3439503,0.04206229,0.005996065,0.003061438,0.0001473293,0.002307642,0.0002480125,0.07367135],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.01373193,"threshold_uncertainty_score":0.0459379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01517968805238338,"score_gpt":0.2934055633311993,"score_spread":0.2782258752788159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}