{"id":"W4238594081","doi":"10.1016/j.jpainsymman.2005.01.007","title":"Hydromorphone","year":2005,"lang":"en","type":"review","venue":"Journal of Pain and Symptom Management","topic":"Pain Management and Opioid Use","field":"Medicine","cited_by":183,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Hydromorphone; Medicine; Toxicity; Opioid; Pharmacokinetics; Chronic pain; Pharmacodynamics; Cancer pain; Pharmacology; Anesthesia; Intrathecal; Morphine; Cancer; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002557605,0.0003617902,0.001730317,0.0007177337,0.00005189072,0.00005942336,0.0002159969,0.0001416954,0.000178419],"category_scores_gemma":[0.00005122665,0.0002521168,0.0006135838,0.0002566086,0.0000478694,0.00007006503,0.0001292899,0.0004068091,0.00005291681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001444146,"about_ca_system_score_gemma":0.00005076639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":7.289697e-7,"about_ca_topic_score_gemma":3.846715e-7,"domain_scores_codex":[0.9977583,0.0002433432,0.001012926,0.0002251762,0.0004930657,0.00026723],"domain_scores_gemma":[0.9985234,0.0001446424,0.0007462304,0.0003088776,0.00005477649,0.0002220631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001424749,0.0001241075,0.00003617658,0.01620768,0.001229553,0.0007806972,0.00003654348,3.620067e-7,4.410149e-8,0.0003085673,0.03298645,0.9482756],"study_design_scores_gemma":[0.0007936626,0.0002860481,0.0001412808,0.01699841,0.003710995,0.0001015599,0.00006861573,0.00003056957,2.245927e-8,0.00003732062,0.9776182,0.0002133606],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001045502,0.9901412,0.0005429835,0.000275207,0.0002460014,0.0006408397,0.000001587428,0.00001900875,0.00812274],"genre_scores_gemma":[0.00001527781,0.9857177,0.002034707,0.0006042563,0.0007913989,0.00001074589,0.00001365452,0.00004283753,0.01076948],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9480622,"threshold_uncertainty_score":0.9999931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02893743391763153,"score_gpt":0.3189670466428471,"score_spread":0.2900296127252156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}