{"id":"W4238609583","doi":"10.1139/y00-110","title":"Uptake properties of lamivudine (3TC) by a continuous renal epithelial cell line","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council","keywords":"Organic cation transport proteins; Cytidine; Chemistry; Nucleoside; Kidney; Tetraethylammonium; Renal physiology; Biophysics; Biochemistry; Pharmacology; Biology; Transporter; Endocrinology; Renal function; Potassium","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003322598,0.000197175,0.0006701585,0.0001782713,0.0003248267,0.0007099197,0.0003875387,0.0005206724,0.0009708239],"category_scores_gemma":[0.0002581464,0.0001666521,0.0004384583,0.000474885,0.0001569408,0.0003062188,0.0001820478,0.0005231876,0.0007523498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004053276,"about_ca_system_score_gemma":0.0003268531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006206416,"about_ca_topic_score_gemma":0.005163392,"domain_scores_codex":[0.9994739,0.00008740791,0.00006729849,0.0000966068,0.0002019936,0.00007282707],"domain_scores_gemma":[0.9996009,0.00009026456,0.00004678185,0.00007686999,0.0001603631,0.00002475033],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000677738,0.00002910173,0.0006321169,0.00005512073,0.000009188812,0.00008033292,0.00004405938,0.00007644294,0.9976947,0.00003905973,0.00003369546,0.001238411],"study_design_scores_gemma":[0.00001383599,0.0007418689,0.01425343,0.00000938686,0.000067734,0.0007078396,0.0001932619,0.002720064,0.9779825,0.00002467342,0.003263134,0.00002223995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807118,0.005579713,0.01060332,0.0001335997,0.00003536186,0.00004761872,0.001080231,0.0001038456,0.00170454],"genre_scores_gemma":[0.9835036,0.002326215,0.008406448,0.0001070242,0.00002305947,0.00005390017,0.001826002,0.00002305619,0.003730625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006206416,"threshold_uncertainty_score":0.01234061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01539542999050898,"score_gpt":0.2453940023310151,"score_spread":0.2299985723405061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}