{"id":"W4238657242","doi":"10.1562/2004-07-23-ra-244.1","title":"Calculation of Singlet Oxygen Dose from Photosensitizer Fluorescence and Photobleaching During mTHPC Photodynamic Therapy of MLL Cells¶","year":2005,"lang":"en","type":"article","venue":"Photochemistry and Photobiology","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre; McMaster University","funders":"","keywords":"Singlet oxygen; Photobleaching; Photosensitizer; Photodynamic therapy; Photochemistry; Chemistry; Fluorescence; Oxygen; Irradiation; Singlet state; Fluence; Viability assay; Biophysics; Cell; Optics; Organic chemistry; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005651817,0.0004936982,0.0004354294,0.0004470535,0.000198177,0.0004273633,0.0004667057,0.0005391632,0.0004109551],"category_scores_gemma":[0.0007199956,0.0002152883,0.0003931712,0.0003272537,0.0002319684,0.0003667227,0.0001859539,0.0006932555,0.000269238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001041185,"about_ca_system_score_gemma":0.0003689022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001719565,"about_ca_topic_score_gemma":0.0009891043,"domain_scores_codex":[0.9997674,0.00003466748,0.00001676381,0.0000348363,0.0001281746,0.00001820399],"domain_scores_gemma":[0.9997161,0.0001320897,0.00006131029,0.00003009178,0.00004729137,0.00001307633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002871548,0.00007091236,0.002577257,0.0001529143,0.00002316574,0.00008830389,0.000100709,0.01952836,0.9597593,0.0009134713,0.0001095641,0.01638889],"study_design_scores_gemma":[0.00001134592,0.000238461,0.003129032,0.000006311827,0.00001726029,0.00007442617,0.00001754505,0.08658553,0.908415,0.0002814123,0.001209277,0.00001454376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8374915,0.002140389,0.1576871,0.00007587731,0.00003643592,0.0001652334,0.0004657762,0.0006129079,0.001324861],"genre_scores_gemma":[0.9612161,0.0007897677,0.03603952,0.00001605302,0.000003994527,0.0001350268,0.0003900818,0.00006949799,0.001339996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001719565,"threshold_uncertainty_score":0.007554412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01104521338497128,"score_gpt":0.2698363601202173,"score_spread":0.258791146735246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}