{"id":"W4238704533","doi":"10.1158/1538-7445.am2019-ct115","title":"Abstract CT115: Phase II study of dianhydrogalactitol (VAL-083) in patients with MGMT-unmethylated, bevacizumab-naïve recurrent glioblastoma","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Delmar (Canada)","funders":"","keywords":"Temozolomide; Bevacizumab; Medicine; Oncology; Internal medicine; Phases of clinical research; Clinical trial; In vivo; Cancer research; Radiation therapy; Chemotherapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007508994,0.001414745,0.001600602,0.0004517382,0.0003603777,0.0008258495,0.0007926233,0.0008339233,0.002445573],"category_scores_gemma":[0.0004480411,0.0004678355,0.0009109866,0.0004825553,0.0007308136,0.0005996181,0.0003106209,0.002479621,0.0008135926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001072944,"about_ca_system_score_gemma":0.001334428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002901658,"about_ca_topic_score_gemma":0.00667175,"domain_scores_codex":[0.9997745,0.00008198024,0.00001287804,0.00005040652,0.0000255479,0.00005469312],"domain_scores_gemma":[0.9997135,0.00002116295,0.00003416457,0.00002238765,0.00002061696,0.0001880997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5313112,0.09321655,0.01346876,0.001364986,0.002980085,0.0007331704,0.0006437797,0.004410167,0.1576177,0.0005763657,0.008734338,0.184943],"study_design_scores_gemma":[0.2696035,0.6892003,0.02536976,0.00005898135,0.000739094,0.0004699433,0.0001346415,0.00208161,0.007836248,0.0002429346,0.004203978,0.00005899451],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934807,0.002180038,0.0004254075,0.0003166779,0.0001183316,0.001206724,0.0007743859,0.0001246381,0.001373106],"genre_scores_gemma":[0.9927067,0.001434395,0.0007385134,0.000590017,0.00007811231,0.0007327501,0.002118085,0.00002549581,0.001575968],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002901658,"threshold_uncertainty_score":0.008181274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03642200463099327,"score_gpt":0.3967372145391351,"score_spread":0.3603152099081419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}