{"id":"W4238807546","doi":"10.1093/ibd/izaa347.087","title":"INHIBITION OF DAPK3, PINPOINTED AS A KEY FACTOR IN THE DEVELOPMENT OF COLITIS-ASSOCIATED DYSPLASIA, INCREASES SEVERITY OF DSS-INDUCED COLITIS VIA HIPPO SIGNALING","year":2021,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Pancolitis; Colitis; Ulcerative colitis; Actin cytoskeleton; Dysplasia; Cancer research; Hippo signaling pathway; Biology; Medicine; Pathology; Signal transduction; Internal medicine; Colorectal cancer; Cancer; Cell; Cell biology; Cytoskeleton; Disease; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009620281,0.0003474806,0.0004355803,0.0005356555,0.0001619346,0.0002955731,0.0001563221,0.0001806484,0.00179754],"category_scores_gemma":[0.00006673434,0.0001373662,0.0002862883,0.0005899309,0.0001949125,0.0001308026,0.0001793971,0.000549717,0.0003433848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002285243,"about_ca_system_score_gemma":0.0001982245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003847144,"about_ca_topic_score_gemma":0.0005769537,"domain_scores_codex":[0.9998487,0.00001106898,0.00001658984,0.00004114448,0.00004426522,0.00003828017],"domain_scores_gemma":[0.9999315,0.000005500298,0.00002688787,0.000005176917,0.000007211262,0.00002375194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007709545,0.00005697979,0.001281255,0.0001594848,0.00001942176,0.00005202814,0.000009263363,0.0001074806,0.9951499,0.00003761805,0.0001771461,0.002178384],"study_design_scores_gemma":[0.00006528066,0.0008591556,0.05289542,0.00002372981,0.00009196291,0.000315008,0.00005813213,0.00182633,0.9394045,0.0001033009,0.004344514,0.00001263403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848455,0.004395627,0.002895011,0.0001246092,0.00005348652,0.00004421495,0.006167985,0.0002963324,0.001177035],"genre_scores_gemma":[0.9856096,0.002747487,0.003275293,0.00007250952,0.00001989021,0.000108311,0.00607051,0.00003147119,0.002064913],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00179754,"threshold_uncertainty_score":0.006013334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01236304967464461,"score_gpt":0.239377326516249,"score_spread":0.2270142768416044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}