{"id":"W4238817388","doi":"10.1182/blood.v118.21.436.436","title":"Whole Transcriptome Sequencing Reveals Recurrent NOTCH1 Mutations in Mantle Cell Lymphoma","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Mantle cell lymphoma; Sanger sequencing; Transcriptome; Biology; Cancer research; Cyclin D1; Lymphoma; Molecular biology; Genetics; Exon; DNA sequencing; Gene; Cell cycle; Immunology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001897084,0.0001941419,0.0002723368,0.0004401292,0.0001805506,0.0004063731,0.0001804561,0.0003632609,0.0006865904],"category_scores_gemma":[0.0003337258,0.000120179,0.0003628148,0.0004053676,0.000141236,0.00008571304,0.0003185226,0.000257337,0.0002308762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002300064,"about_ca_system_score_gemma":0.0001136361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005854783,"about_ca_topic_score_gemma":0.001278708,"domain_scores_codex":[0.9998581,0.00001403279,0.00000986956,0.00005292747,0.00003585274,0.00002914338],"domain_scores_gemma":[0.9998215,0.00005728965,0.00003853523,0.00002930643,0.00002607787,0.00002736421],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0009022425,0.00007506776,0.1307666,0.0001676779,0.0001405379,0.001798899,0.000436472,0.0007611997,0.844894,0.00008736952,0.0008482706,0.01912178],"study_design_scores_gemma":[0.0000950396,0.000523277,0.8494487,0.00006573916,0.0004395073,0.007274067,0.0008623454,0.006762308,0.1259955,0.0003496078,0.008156838,0.00002697348],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997165,0.0002516837,0.0007905081,0.00002804926,0.000003176538,0.00000777529,0.001556127,0.00002964706,0.000167959],"genre_scores_gemma":[0.9920552,0.0002013644,0.001763237,0.00007259504,0.000007034894,0.00002044412,0.0054859,0.00002643597,0.0003677477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006865904,"threshold_uncertainty_score":0.002296865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03791925599566054,"score_gpt":0.2533030348417356,"score_spread":0.215383778846075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}