{"id":"W4239096216","doi":"10.1002/ange.202012444","title":"Selection and Characterization of an RNA‐Cleaving DNAzyme Activated by <i>Legionella pneumophila</i>","year":2020,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Legionella pneumophila; Deoxyribozyme; Microbiology; Legionella; Legionnaires' disease; RNA; Biology; Chemistry; Bacteria; Virology; Biochemistry; Gene; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002277057,0.0003997508,0.0002097235,0.000202909,0.00008831766,0.0002758135,0.000210106,0.0003241737,0.0006762926],"category_scores_gemma":[0.0003953993,0.00009888419,0.0002338503,0.0001647064,0.0001465879,0.0001253246,0.0001248033,0.0002844154,0.0004726917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00016278,"about_ca_system_score_gemma":0.0001422195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003100806,"about_ca_topic_score_gemma":0.0002501617,"domain_scores_codex":[0.9997906,0.00004191742,0.00001714837,0.00005715571,0.00005385097,0.00003930645],"domain_scores_gemma":[0.9997274,0.00006210657,0.0000785669,0.00002599026,0.00005628203,0.00004973015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001152084,0.00001105842,0.00008276168,0.00001020517,0.000001209514,0.00001484238,0.000004825727,0.00002626197,0.9992786,0.00001193204,0.000008959913,0.0005378263],"study_design_scores_gemma":[0.000003267029,0.0001203675,0.0009567105,0.000001887318,0.000003738462,0.00009111916,0.00000813426,0.0002300258,0.9980274,0.000006353628,0.0005488354,0.000002284077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9805416,0.0005033222,0.01698281,0.0001273365,0.00002638507,0.00008379708,0.0005141557,0.0001108998,0.001109615],"genre_scores_gemma":[0.979337,0.0003096705,0.01594233,0.00006293414,0.000009547706,0.0000665468,0.001586402,0.00004639862,0.002639148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006762926,"threshold_uncertainty_score":0.002262473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00938381909490201,"score_gpt":0.2327142929594149,"score_spread":0.2233304738645129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}