{"id":"W4239340399","doi":"10.1111/j.1574-6968.2004.tb09768.x","title":"Cholesterol and the activity of bacterial toxins","year":2004,"lang":"en","type":"article","venue":"FEMS Microbiology Letters","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Cytolysin; Vibrio cholerae; Toxin; Microbiology; Cholesterol; Microbial toxins; Staphylococcus aureus; Bacteria; Hemolysin; Diphtheria toxin; Biology; Membrane fluidity; Pore-forming toxin; Chemistry; Biochemistry; Membrane; Virulence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003046795,0.0002230613,0.0002638758,0.0005503037,0.0003109409,0.0008486062,0.000211873,0.0006207547,0.0007978829],"category_scores_gemma":[0.0008587869,0.00009745326,0.0001514606,0.0004558364,0.0004991174,0.0003332988,0.0005251259,0.0005006464,0.0003589686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008839829,"about_ca_system_score_gemma":0.0004541992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001548845,"about_ca_topic_score_gemma":0.001093565,"domain_scores_codex":[0.9996468,0.00006853717,0.0000253836,0.00002777989,0.0001297871,0.0001017654],"domain_scores_gemma":[0.9995995,0.00009934619,0.00009303332,0.00002603679,0.0000957541,0.00008623398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001575637,0.0001820028,0.01210372,0.0008569876,0.00008159807,0.002536447,0.0004227463,0.001856516,0.8796225,0.04041701,0.00118259,0.05916221],"study_design_scores_gemma":[0.0001095267,0.001118909,0.06066907,0.0003015903,0.0001057886,0.003265729,0.0006197439,0.003070879,0.8215424,0.02626396,0.08287644,0.00005610992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8306497,0.1313724,0.002693522,0.00204294,0.0002421879,0.00003813257,0.0002131447,0.00003888334,0.03270909],"genre_scores_gemma":[0.9658797,0.02608821,0.0005014189,0.0001504742,0.0001304501,0.00001382474,0.0001409646,0.000004017538,0.007091021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001548845,"threshold_uncertainty_score":0.006413758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004801956166356833,"score_gpt":0.2067755194454433,"score_spread":0.2019735632790865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}