{"id":"W4239376443","doi":"10.1155/2010/268452","title":"C-terminal domain of nonhistone protein HMGB1 as a modulator of HMGB1–DNA structural interactions","year":2010,"lang":"en","type":"article","venue":"Spectroscopy An International Journal","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Russian Foundation for Basic Research; University of Calgary","keywords":"HMGB1; DNA; Circular dichroism; High-mobility group; Biophysics; Chemistry; Crystallography; Biochemistry; Biology; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002309235,0.0001308599,0.0001448205,0.0001743598,0.00008313768,0.00003591707,0.0005554283,0.0000729811,0.0006770761],"category_scores_gemma":[0.000218934,0.0001235121,0.0001042849,0.00008120327,0.0002106832,0.00005049877,0.00009185325,0.0004316565,0.000007300158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004640362,"about_ca_system_score_gemma":0.0002643062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002567272,"about_ca_topic_score_gemma":0.00004792269,"domain_scores_codex":[0.9986478,0.00006357863,0.0003959913,0.0002455096,0.0004553807,0.0001917219],"domain_scores_gemma":[0.9985607,0.000009190665,0.0003441119,0.0003054398,0.0006549649,0.000125645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004866557,0.00009540798,0.0008178339,0.000007055319,0.00007967912,0.00001085715,0.0001037428,0.00004941343,0.9942078,0.002937348,0.00006335975,0.001140853],"study_design_scores_gemma":[0.0005501804,0.0004589428,0.003721273,0.00002169532,0.000006389033,0.0007665809,0.00008227027,0.00006271271,0.9841558,0.00602012,0.004034159,0.0001198503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935125,0.00003088136,0.003995395,0.0003680328,0.0008377563,0.0001441989,0.00004595583,0.000005439494,0.001059829],"genre_scores_gemma":[0.9707549,0.000019339,0.0273881,0.00003378653,0.00102633,0.000008521011,0.00006203919,0.00001947275,0.0006874696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02339271,"threshold_uncertainty_score":0.7413509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008115919490877869,"score_gpt":0.3611095401618347,"score_spread":0.3529936206709569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}