{"id":"W4239376504","doi":"10.1182/blood-2019-122506","title":"Dynamic and Time-to-Event Analyses Demonstrate Marked Reduction in Transfusion Requirements for Janus Kinase Inhibitor-Naïve Myelofibrosis Patients Treated with Momelotinib Compared Head to Head with Ruxolitinib","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sierra Wireless (Canada)","funders":"","keywords":"Ruxolitinib; Anemia; Myelofibrosis; Medicine; Hepcidin; Internal medicine; Gastroenterology; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005765029,0.0002198641,0.001201448,0.0003389552,0.0001570696,0.000497914,0.0001802477,0.0002787213,0.00314969],"category_scores_gemma":[0.001094282,0.0001155157,0.0006902299,0.0003231548,0.0001018452,0.0003132086,0.000160625,0.0009329102,0.00025316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002635758,"about_ca_system_score_gemma":0.000290084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007501803,"about_ca_topic_score_gemma":0.001664538,"domain_scores_codex":[0.9997216,0.00006161373,0.00003083315,0.000072361,0.00006830601,0.00004529367],"domain_scores_gemma":[0.9992822,0.0001926034,0.0002366066,0.00004405909,0.00005640416,0.000188297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1874738,0.00328482,0.433674,0.0005052951,0.003004917,0.001191996,0.000318713,0.003346826,0.06883431,0.000587704,0.007415987,0.2903616],"study_design_scores_gemma":[0.002087093,0.01709582,0.9639763,0.00004021214,0.001123987,0.001172431,0.0001057207,0.00377898,0.006068029,0.0004721546,0.004029489,0.00004977342],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936434,0.00183838,0.0004658078,0.0001700644,0.00003306335,0.00005477652,0.001654304,0.0000626359,0.002077513],"genre_scores_gemma":[0.9974781,0.0002480634,0.0002764553,0.0001327203,0.00002805424,0.00003542065,0.001148539,0.000006248439,0.0006463958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00314969,"threshold_uncertainty_score":0.01053673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02246425433949222,"score_gpt":0.3030663069986346,"score_spread":0.2806020526591423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}