{"id":"W4239497743","doi":"10.25011/cim.v30i4.2881","title":"Regulation of huntingtin palmitoylation and its role in Huntington Diseases","year":2007,"lang":"en","type":"article","venue":"Clinical and investigative medicine","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Palmitoylation; Huntingtin; Polyglutamine tract; Huntingtin Protein; Cell biology; Huntington's disease; Biology; Mutation; Mutant; Neuroscience; Genetics; Cysteine; Biochemistry; Gene; Internal medicine; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002677226,0.000294576,0.0002509843,0.0002560377,0.0003140332,0.0004828585,0.000228598,0.000438525,0.0006287001],"category_scores_gemma":[0.0001448631,0.0001035253,0.0002343661,0.0002114228,0.0004093405,0.0003752273,0.0004447376,0.0002457244,0.0002463021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006136333,"about_ca_system_score_gemma":0.0001794684,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001063274,"about_ca_topic_score_gemma":0.001089054,"domain_scores_codex":[0.9998733,0.00002562108,0.00001645805,0.00003539742,0.00002929555,0.00001985536],"domain_scores_gemma":[0.9998941,0.00001155717,0.00003365118,0.000007858738,0.00003045093,0.00002240686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004167525,0.00003984505,0.001492864,0.0001339509,0.00001610915,0.0004290735,0.00008355327,0.0002362849,0.9910794,0.0007530754,0.0001304965,0.005188649],"study_design_scores_gemma":[0.00006365868,0.0004930323,0.0869509,0.00006852754,0.00006926123,0.001490999,0.000222687,0.003274422,0.8864521,0.001698251,0.01917529,0.00004094968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9510961,0.03904961,0.004920063,0.0005300372,0.00008140199,0.00004352719,0.0003812988,0.00007207236,0.003825859],"genre_scores_gemma":[0.9815789,0.01283494,0.002092741,0.0001476836,0.00003974214,0.00003267104,0.0004500506,0.00001336581,0.002809891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001063274,"threshold_uncertainty_score":0.004452229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.116695650481024,"score_gpt":0.3460194228865789,"score_spread":0.2293237724055548,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}