{"id":"W4239537909","doi":"10.21203/rs.3.rs-131863/v1","title":"Quality and Methodology of Clinical Practice Guidelines on Antiviral Pharmacotherapy for COVID-19 During the Early Phase of the Pandemic","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Pharmacy and Medical Practices","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Impact","funders":"","keywords":"Pandemic; Coronavirus disease 2019 (COVID-19); Pharmacotherapy; 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Quality (philosophy); Phase (matter); Virology; Medicine; Clinical Practice; Intensive care medicine; Family medicine; Internal medicine; Chemistry; Disease; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":["metaresearch"],"domain":"evaluation","study_design":"observational","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"high","status":"direct model label, unvalidated"},{"model":"gpt","categories":["metaresearch"],"domain":"evaluation","study_design":"systematic_review","genre":"review","about_ca_system":false,"about_ca_topic":false,"confidence":"high","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.4173192,0.001206395,0.002374632,0.01040153,0.003523348,0.01722321,0.006147798,0.006589625,0.003319259],"category_scores_gemma":[0.6331058,0.001813197,0.00302758,0.00942161,0.004346685,0.003878479,0.007190366,0.007849863,0.001807297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01795417,"about_ca_system_score_gemma":0.1216694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02893643,"about_ca_topic_score_gemma":0.02222586,"domain_scores_codex":[0.4343602,0.3694735,0.104978,0.009358289,0.07596413,0.00586582],"domain_scores_gemma":[0.2128691,0.3489867,0.07216441,0.06114332,0.2956654,0.009171092],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0006832352,0.001081677,0.04853293,0.01388413,0.001172314,0.0006293807,0.02269678,0.009927792,0.002643071,0.08537336,0.1732129,0.6401625],"study_design_scores_gemma":[0.001345938,0.001458828,0.1113627,0.07432343,0.001655565,0.001160661,0.01618767,0.02570402,0.01439712,0.08719739,0.6644433,0.000763395],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.0440359,0.02813739,0.5185347,0.236275,0.01183839,0.05254195,0.01214904,0.00317658,0.09331115],"genre_scores_gemma":[0.1715381,0.007534548,0.775694,0.01255811,0.0015512,0.02017152,0.006039445,0.0006218922,0.004291214],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.5826808,"threshold_uncertainty_score":0.7185492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.9238040585296279,"score_gpt":0.793024743886697,"score_spread":0.1307793146429309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}