{"id":"W4239611289","doi":"10.1515/iupac.79.1587","title":"Maximum Tolerated Dose (MTD)","year":2016,"lang":"en","type":"dataset","venue":"IUPAC Standards Online","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Glossary; Chemical nomenclature; Toxicology; Hazard; Computer science; Chemistry; Philosophy; Biology; Linguistics; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003305458,0.0005148184,0.0005041763,0.0001114766,0.0001187278,0.00006903029,0.0004587506,0.0006590323,0.001438768],"category_scores_gemma":[0.0001293203,0.000411969,0.0002730101,0.0001169211,0.0001284753,0.000002995997,0.0003743929,0.0002796933,0.000004067928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001516771,"about_ca_system_score_gemma":0.000918415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009390898,"about_ca_topic_score_gemma":0.001066618,"domain_scores_codex":[0.9975245,0.00008938734,0.000439121,0.0007758571,0.0006515131,0.0005196176],"domain_scores_gemma":[0.9979104,0.00001214169,0.0002190273,0.001165038,0.0004785784,0.000214771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002882592,0.0002108955,0.000008773983,0.00006542946,0.0001915248,0.00005618536,0.000002221107,0.000003228692,0.01604894,0.000001529264,0.9801989,0.002924092],"study_design_scores_gemma":[0.001212825,0.0005482521,0.00005871403,0.00009686055,0.00009437028,0.0000337406,0.00001259239,0.000001743381,0.005457567,0.00003777093,0.9918761,0.0005694157],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.003795694,0.001362405,0.0002839879,0.0003757805,0.0006598312,0.0003542726,0.9930714,0.00002227368,0.00007440399],"genre_scores_gemma":[0.0004510356,0.001808152,0.00006659701,0.0006376929,0.001539283,0.00002706045,0.9943957,0.00005348794,0.001020984],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.01167722,"threshold_uncertainty_score":0.9998332,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01128805212490874,"score_gpt":0.3756922389225381,"score_spread":0.3644041867976294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}