{"id":"W4239676748","doi":"10.26434/chemrxiv.5972863.v1","title":"Designing Stability into Thermally Reactive Plumbylenes","year":2018,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Chemistry; Transamination; Thermal stability; Imine; Medicinal chemistry; Acetoin; Intramolecular force; Detonation; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00111884,0.000757917,0.0008322901,0.00004086248,0.0001543819,0.0001253187,0.001321065,0.001245783,0.01411287],"category_scores_gemma":[0.00186618,0.0007980621,0.0003800148,0.0001197776,0.0005512706,0.000072746,0.001738675,0.001409741,0.000145282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000686501,"about_ca_system_score_gemma":0.0005760334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001254476,"about_ca_topic_score_gemma":0.000005643272,"domain_scores_codex":[0.9965076,0.0001136328,0.0007005327,0.0015769,0.0005068317,0.0005944956],"domain_scores_gemma":[0.9955451,0.0006767629,0.0005679645,0.002616944,0.0003306275,0.000262523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006016596,0.0001314737,0.001653084,0.001234981,0.0002119377,0.00001312065,0.001778085,0.00000156357,0.9909106,0.000003224136,0.0003421265,0.003659655],"study_design_scores_gemma":[0.0002825987,0.000007504258,0.0001297128,0.0004439833,0.0001505264,0.00001450935,0.000632074,0.00007331797,0.9912459,0.004688061,0.001544029,0.0007877488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9125916,0.0004769423,0.00243136,0.000191848,0.0004774508,0.0001733816,0.00001302651,0.0005447401,0.08309969],"genre_scores_gemma":[0.9472672,0.00004993602,0.04974764,0.00004087855,0.001648003,0.0001405427,0.00007063079,0.0001902688,0.0008449316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08225476,"threshold_uncertainty_score":0.999447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04512249694703126,"score_gpt":0.3029259910877652,"score_spread":0.2578034941407339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}