{"id":"W4239696157","doi":"10.22215/etd/2021-14339","title":"Biotransformation of 8:2 Monosubstituted Polyfluoroalkyl Phosphate in Rat &amp; Human Liver, Intestine, and Fecal in Vitro Suspensions","year":2021,"lang":"en","type":"dissertation","venue":"","topic":"Per- and polyfluoroalkyl substances research","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Biotransformation; Chemistry; Hydrolysis; Phosphate; Metabolism; Biochemistry; Bioaccumulation; Enzyme; Environmental chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001222403,0.0003662364,0.0001250686,0.000145993,0.00008901028,0.0001486578,0.0000851255,0.0001570749,0.001300068],"category_scores_gemma":[0.00008110527,0.00014411,0.0002624274,0.00009413503,0.0001013995,0.0001199243,0.00007374849,0.0002190526,0.0004486472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002170838,"about_ca_system_score_gemma":0.0003206093,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004732926,"about_ca_topic_score_gemma":0.004572434,"domain_scores_codex":[0.9999324,0.00001145708,0.000004031784,0.00001861254,0.00001208093,0.00002144162],"domain_scores_gemma":[0.999966,0.000007396198,0.000007861582,0.000004412569,0.000008623734,0.000005658183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002973506,0.000052837,0.0004164804,0.00005253512,0.000007685015,0.00008881012,0.00002392769,0.0001736961,0.9949718,0.00006428193,0.00004475054,0.003805882],"study_design_scores_gemma":[0.000008720244,0.0007008153,0.002427253,0.000004101755,0.0000156019,0.000100458,0.00001915095,0.000278632,0.9956958,0.00001433827,0.0007320136,0.000003099233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938754,0.001617286,0.002193348,0.00003538058,0.00002530137,0.00003592081,0.0004172452,0.00003858286,0.001761485],"genre_scores_gemma":[0.9876649,0.001595374,0.001515633,0.00002730781,0.000009112596,0.00003548303,0.000618499,0.0000124387,0.008521358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004732926,"threshold_uncertainty_score":0.009410799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02020056100999081,"score_gpt":0.2890034941256949,"score_spread":0.2688029331157041,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}