{"id":"W4239776133","doi":"10.1126/stke.2000.23.re1","title":"Crossing Smads","year":2000,"lang":"en","type":"review","venue":"Science s STKE","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"SMAD; R-SMAD; Cell biology; Signal transduction; Phosphorylation; Smad2 Protein; Crosstalk; Transcription factor; Biology; TGF beta receptor 2; Chemistry; Endoglin; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00145785,0.001185915,0.0006716208,0.001329264,0.001207108,0.003077887,0.001198664,0.001876264,0.07773233],"category_scores_gemma":[0.002354346,0.0005697933,0.0009762843,0.0007931379,0.001210088,0.001723368,0.002654128,0.002888608,0.02333526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000949687,"about_ca_system_score_gemma":0.001796779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007457173,"about_ca_topic_score_gemma":0.0009318388,"domain_scores_codex":[0.9986028,0.0003000933,0.0000941296,0.0003134426,0.0004911864,0.0001983135],"domain_scores_gemma":[0.9988661,0.0002493537,0.0001792639,0.0001579856,0.0003123983,0.0002349594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008840902,0.0001393248,0.001993141,0.002789972,0.0003388468,0.001949003,0.0007644683,0.001509529,0.05210998,0.3565403,0.1764081,0.4045733],"study_design_scores_gemma":[0.00006795178,0.00007555314,0.0004512926,0.0002414933,0.00007166031,0.001526206,0.0001438519,0.0003320541,0.007104486,0.02418906,0.9657676,0.00002882213],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.03964147,0.07541724,0.169456,0.02737998,0.03207729,0.0005857855,0.008174474,0.007357372,0.6399103],"genre_scores_gemma":[0.3623797,0.07722717,0.09294277,0.02567246,0.007102641,0.0009334189,0.01387853,0.002578659,0.4172847],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.07773233,"threshold_uncertainty_score":0.2600405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03613545246660631,"score_gpt":0.3735665354689152,"score_spread":0.3374310830023089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}