{"id":"W4239926224","doi":"10.22215/etd/2021-14447","title":"Characterization and Application of a Histamine Aptamer-Based Biosensor","year":2021,"lang":"en","type":"dissertation","venue":"","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Aptamer; Biosensor; Histamine; Chemistry; Chromatography; Biology; Computational biology; Biochemistry; Pharmacology; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002778887,0.0003476526,0.000263943,0.0001976747,0.0001704812,0.0004322034,0.0006473455,0.000994875,0.001184282],"category_scores_gemma":[0.0003269107,0.0001932681,0.0002767488,0.0001734737,0.0001390247,0.0002934601,0.000241625,0.0005010833,0.001017943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002567033,"about_ca_system_score_gemma":0.0001762858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002790691,"about_ca_topic_score_gemma":0.0003603314,"domain_scores_codex":[0.9996789,0.00002670401,0.00001355372,0.00008721813,0.0001566409,0.00003705516],"domain_scores_gemma":[0.9998767,0.00002554249,0.00001647363,0.00001120515,0.00005115629,0.00001894021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008973759,0.00001322072,0.00002526331,0.00001326806,0.000001787896,0.00001884567,0.000007615023,0.00004347311,0.9986063,0.00004274577,0.00004405962,0.001174588],"study_design_scores_gemma":[0.000003074453,0.0001033978,0.0003616516,0.000002148153,0.00000546766,0.0001171822,0.000009911329,0.001519459,0.9959279,0.00002794628,0.001917687,0.000004195728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.7826899,0.004423045,0.1961141,0.001125728,0.0005122676,0.0004641223,0.0006632335,0.0008808288,0.01312676],"genre_scores_gemma":[0.8977652,0.001895009,0.07744466,0.0004837899,0.00005949634,0.00019299,0.0008845797,0.00008683249,0.02118747],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001184282,"threshold_uncertainty_score":0.003961802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005291858050013846,"score_gpt":0.2141391788796877,"score_spread":0.2088473208296739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}