{"id":"W4240088577","doi":"10.1007/978-3-319-28845-1_5222-1","title":"Li-Fraumeni Syndrome","year":2020,"lang":"en","type":"book-chapter","venue":"Encyclopedia of pathology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Li–Fraumeni syndrome; History; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001212537,0.0004937102,0.001330852,0.0002923129,0.00002969798,0.000003397147,0.0002308631,0.001085429,0.001950458],"category_scores_gemma":[0.0001512932,0.0005103161,0.0004344507,0.00006871971,0.000294008,0.00002724935,0.0001971221,0.001147182,0.001175338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000120622,"about_ca_system_score_gemma":0.0004490792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005755629,"about_ca_topic_score_gemma":0.000006143418,"domain_scores_codex":[0.9977688,0.00003333588,0.0007266307,0.0007352217,0.0004016475,0.0003343662],"domain_scores_gemma":[0.9983052,0.00006472717,0.0004231782,0.0007979323,0.0001303408,0.0002786447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001869246,0.0007073699,0.0006092823,0.005088604,0.003510052,0.3985156,0.003730395,0.00003709329,0.02239954,0.273625,0.1979365,0.09197138],"study_design_scores_gemma":[0.001574888,0.001909484,0.0004073004,0.0004953917,0.0009036554,0.008801978,0.00001252881,0.000006417903,0.0002228371,0.005838229,0.9792683,0.0005589596],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.001444284,0.004326,0.0002589985,0.001016478,0.001315503,0.0007249774,0.0001578291,0.0001546818,0.9906012],"genre_scores_gemma":[0.02201787,0.01050439,0.004223651,0.002000071,0.001254931,0.00007285637,0.0007364228,0.0005358172,0.958654],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.7813318,"threshold_uncertainty_score":0.9997348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01300168696748445,"score_gpt":0.235368830847472,"score_spread":0.2223671438799875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}