{"id":"W4240088577","doi":"10.1007/978-3-319-28845-1_5222-1","title":"Li-Fraumeni Syndrome","year":2020,"lang":"en","type":"book-chapter","venue":"Encyclopedia of pathology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Li–Fraumeni syndrome; History; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008994638,0.0005889718,0.0002801933,0.001008773,0.0003583283,0.0005990972,0.0003429284,0.0005839485,0.04655186],"category_scores_gemma":[0.0002499831,0.0001437617,0.0001818398,0.0006929847,0.0003235019,0.0006545207,0.0005718651,0.0008689832,0.01668453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004111162,"about_ca_system_score_gemma":0.0003435569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007680532,"about_ca_topic_score_gemma":0.002510734,"domain_scores_codex":[0.999952,0.000005348965,0.000002416939,0.000008596492,0.00002445141,0.000007290607],"domain_scores_gemma":[0.9999603,0.00001820771,0.000003302222,0.000003501319,0.000006422614,0.000008218323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002843618,0.00002746311,0.0003233077,0.0002384527,0.000009441651,0.004566188,0.0002145488,0.000270295,0.002977413,0.06419863,0.4467509,0.4803948],"study_design_scores_gemma":[0.00000252111,0.000007428308,0.0002340247,0.00008172179,0.000002686329,0.006539518,0.00002434531,0.00004039042,0.0002761485,0.004904793,0.9878829,0.000003475481],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.003002746,0.1156084,0.005496165,0.004037889,0.004262179,0.00003790991,0.0003897008,0.0004439154,0.8667211],"genre_scores_gemma":[0.01138291,0.05125284,0.00330368,0.001833709,0.000884305,0.00003698291,0.0003518569,0.00009063524,0.9308631],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.04655186,"threshold_uncertainty_score":0.1557314,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01300168696748445,"score_gpt":0.235368830847472,"score_spread":0.2223671438799875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}