{"id":"W4240143686","doi":"10.3410/f.1024040.285853","title":"Faculty Opinions recommendation of Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception.","year":2005,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Centre National de la Recherche Scientifique","keywords":"Nociception; Dorsal root ganglion; T-type calcium channel; Gene knockdown; Voltage-dependent calcium channel; Calcium channel; Sensory system; Gene silencing; Medicine; Pharmacology; Neuroscience; Chronic pain; Calcium; Chemistry; Biology; Receptor; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001118908,0.0008512106,0.0005479684,0.004134033,0.0004425349,0.001295695,0.0008759229,0.0005568901,0.09552396],"category_scores_gemma":[0.008466625,0.000217226,0.0005075843,0.007259595,0.0001835924,0.0008269023,0.0005973974,0.0008310648,0.03899891],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001046239,"about_ca_system_score_gemma":0.00249082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01415834,"about_ca_topic_score_gemma":0.02762096,"domain_scores_codex":[0.9988456,0.0001598912,0.0001088225,0.0002271856,0.0005632296,0.00009528922],"domain_scores_gemma":[0.9956915,0.001218953,0.0006445213,0.0005968023,0.001424976,0.0004233589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001778331,0.00004363652,0.009763137,0.001039753,0.00008104608,0.0001133691,0.00006677498,0.0006540886,0.001901994,0.0008988089,0.9325342,0.05272541],"study_design_scores_gemma":[0.00009825512,0.00002837828,0.02749603,0.0001562418,0.00005600645,0.0001161454,0.00009292756,0.001889021,0.003566596,0.0005082101,0.9659678,0.00002445831],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"dataset","genre_scores_codex":[0.006877702,0.0004065898,0.001212666,0.001020033,0.0002244391,0.0000822638,0.9600972,0.002157952,0.02792118],"genre_scores_gemma":[0.01485528,0.0005539564,0.003255933,0.000194633,0.00006850031,0.0001287331,0.9643582,0.0004138527,0.01617106],"genre_candidate":"dataset","genre_consensus":"dataset","teacher_disagreement_score":0.09552396,"threshold_uncertainty_score":0.3195595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03244193509802422,"score_gpt":0.3283651584833614,"score_spread":0.2959232233853372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}