{"id":"W4240152444","doi":"10.21203/rs.3.rs-78815/v1","title":"Surfactant Therapy for COVID-19 Related ARDS: A Retrospective Case-Control Pilot Study.","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Bill and Melinda Gates Foundation","keywords":"ARDS; Coronavirus disease 2019 (COVID-19); Pulmonary surfactant; Surfactant therapy; 2019-20 coronavirus outbreak; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Retrospective cohort study; Medicine; Pandemic; Intensive care medicine; Virology; Internal medicine; Lung; Engineering; Chemical engineering; Infectious disease (medical specialty); Disease; Biology; Outbreak","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001687305,0.0006571587,0.000937007,0.0009958906,0.00107085,0.0008085002,0.000596337,0.001197124,0.00377099],"category_scores_gemma":[0.005273469,0.0005912171,0.0005648402,0.0007898468,0.001118874,0.0008209007,0.0006981755,0.0006090832,0.0009217906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006253339,"about_ca_system_score_gemma":0.001051458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003334282,"about_ca_topic_score_gemma":0.002081769,"domain_scores_codex":[0.9983454,0.0006595944,0.0002195755,0.0004009572,0.0001818794,0.0001926726],"domain_scores_gemma":[0.9971399,0.001092915,0.0006193354,0.0004024895,0.000403119,0.0003423382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0212743,0.01453965,0.9325523,0.0005232937,0.0005323724,0.007955862,0.001964565,0.0001052343,0.005633078,0.0003057625,0.0008114042,0.01380221],"study_design_scores_gemma":[0.003310885,0.08132225,0.8905059,0.0001515281,0.000893216,0.0153651,0.003747507,0.0005075809,0.001321401,0.0002402575,0.002533186,0.0001012476],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978095,0.0007503004,0.0002861184,0.00002969391,0.00001930103,0.0003739629,0.0002274756,0.000005019566,0.0004985909],"genre_scores_gemma":[0.9977089,0.0005827884,0.0004212694,0.00008951339,0.0000599475,0.0002493129,0.0004669698,0.000004670459,0.0004166542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00377099,"threshold_uncertainty_score":0.0126152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2106803866405004,"score_gpt":0.4610416737709065,"score_spread":0.2503612871304062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}