{"id":"W4240218353","doi":"10.22215/etd/2014-10286","title":"Screening the Structure and Binding Affinity of Ochratoxin A Aptamers","year":2014,"lang":"en","type":"dissertation","venue":"","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Aptamer; Ochratoxin A; Oligonucleotide; Mycotoxin; Chemistry; Ochratoxin; Affinity chromatography; Computational biology; Chromatography; Systematic evolution of ligands by exponential enrichment; DNA; Biotechnology; RNA; Biology; Molecular biology; Biochemistry; Food science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004755582,0.0004685303,0.0004055052,0.0003754293,0.0001912955,0.0003185843,0.000387331,0.0008353859,0.001464139],"category_scores_gemma":[0.0009502405,0.0003147226,0.000354312,0.0003031268,0.00020275,0.0002370074,0.0002424396,0.0005603608,0.0008024823],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003625507,"about_ca_system_score_gemma":0.0001447722,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005384483,"about_ca_topic_score_gemma":0.0008356686,"domain_scores_codex":[0.9992893,0.0001478722,0.0000505026,0.0001721313,0.0002277707,0.0001124164],"domain_scores_gemma":[0.9994973,0.0002275985,0.00006728679,0.00003192197,0.0001113844,0.00006445089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004037496,0.00004127889,0.0002051667,0.00003140123,0.000004936308,0.00001613494,0.00001485713,0.000321032,0.9980567,0.00001739441,0.00002795177,0.00122283],"study_design_scores_gemma":[0.00001420949,0.0007050968,0.002072747,0.000006939822,0.00002485893,0.0001037044,0.00002982497,0.002785609,0.9926302,0.00003939059,0.001576574,0.00001080008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9807419,0.002218124,0.01300178,0.0001471264,0.00005067522,0.0001880023,0.00039318,0.0001288649,0.003130385],"genre_scores_gemma":[0.9752009,0.001111534,0.01666298,0.0003072674,0.00001993792,0.0001636256,0.001090225,0.00003825334,0.005405228],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001464139,"threshold_uncertainty_score":0.004898012,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006946585435743296,"score_gpt":0.2693706996264504,"score_spread":0.2624241141907071,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}