{"id":"W4240297670","doi":"10.1016/j.cub.2020.01.044","title":"AAA+ proteins","year":2020,"lang":"en","type":"article","venue":"Current Biology","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Biology; Computational biology; Evolutionary biology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003604565,0.001148257,0.000631498,0.0006583278,0.001406553,0.00180584,0.0007686133,0.001371798,0.02061795],"category_scores_gemma":[0.0005833702,0.0003346654,0.0008888303,0.0007330047,0.0003277111,0.001132192,0.0008236419,0.001070434,0.03248152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006775222,"about_ca_system_score_gemma":0.0005281719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007975036,"about_ca_topic_score_gemma":0.0005057226,"domain_scores_codex":[0.9996075,0.00002397509,0.00002878674,0.0001502815,0.0001194096,0.00007004908],"domain_scores_gemma":[0.9996957,0.00002228096,0.00003975767,0.00005729774,0.00008747284,0.00009756746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001026883,0.0002810161,0.003929268,0.00117367,0.0001613907,0.0009829795,0.0001923267,0.0002781605,0.7489331,0.02352595,0.1179937,0.1015214],"study_design_scores_gemma":[0.00003421549,0.0001437723,0.009125179,0.00005632176,0.00007970572,0.002985119,0.0001326341,0.001243232,0.2466338,0.003676925,0.7358357,0.00005344049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4550881,0.03305243,0.09580406,0.007919513,0.01408378,0.0005256436,0.0312377,0.02084028,0.3414485],"genre_scores_gemma":[0.5120586,0.01304202,0.04049369,0.004212149,0.001596979,0.0002216642,0.07104472,0.0008274565,0.3565027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02061795,"threshold_uncertainty_score":0.06897396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04713441519217326,"score_gpt":0.3340367993764388,"score_spread":0.2869023841842656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}