{"id":"W4240364009","doi":"10.1038/clpt.2014.133","title":"Biotransformation","year":2014,"lang":"en","type":"editorial","venue":"Clinical Pharmacology & Therapeutics","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Clinical pharmacology; Clinical trial; Medicine; Drug development; Human immunodeficiency virus (HIV); Drug; Intensive care medicine; Pharmaceutical industry; Public health; Pharmacology; Virology; Internal medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002024385,0.002066414,0.001318213,0.001524388,0.0007908906,0.003291692,0.001832279,0.005875638,0.02252968],"category_scores_gemma":[0.004667889,0.0005734283,0.001143265,0.001184498,0.002094374,0.004095825,0.002192232,0.007354364,0.02685743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002062988,"about_ca_system_score_gemma":0.001955324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001137216,"about_ca_topic_score_gemma":0.0016295,"domain_scores_codex":[0.997722,0.0003722439,0.0002590767,0.0003016297,0.00120694,0.00013808],"domain_scores_gemma":[0.9983481,0.0004911434,0.0002275939,0.000193437,0.0006052703,0.0001344747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006052619,0.00003720974,0.00004764353,0.001317059,0.00003605646,0.0004824389,0.00005836656,0.0001872354,0.002316352,0.008898005,0.8469397,0.1396194],"study_design_scores_gemma":[0.000004739885,0.00000947635,0.00002477972,0.00007977158,0.000004627239,0.0001906582,0.00000528347,0.00001721405,0.0005940773,0.0008196214,0.998246,0.000003829408],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.0005827054,0.3115506,0.004123216,0.05366556,0.5409926,0.0001190287,0.0005111032,0.0005237939,0.08793145],"genre_scores_gemma":[0.009874929,0.4006247,0.002987075,0.06117977,0.1941762,0.0001494738,0.0008245045,0.0004654248,0.3297179],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.02252968,"threshold_uncertainty_score":0.0753693,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1317251193918982,"score_gpt":0.5186376197035598,"score_spread":0.3869125003116616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}