{"id":"W4240529987","doi":"10.22215/etd/2013-09898","title":"Role of Akt Signaling and its Downstream Pathways in Wood Frog Freeze Tolerance","year":2013,"lang":"en","type":"dissertation","venue":"","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Carleton University","funders":"","keywords":"Protein kinase B; Signal transduction; Biology; Cell biology; PI3K/AKT/mTOR pathway; Intracellular; Cryoprotectant; Cryopreservation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001473837,0.0003124275,0.0001483511,0.0003023112,0.0004279518,0.0006039364,0.0001403551,0.0002321851,0.002585631],"category_scores_gemma":[0.00006914748,0.0001265096,0.0002998367,0.0002394032,0.0002108728,0.000301952,0.0002345109,0.0007547587,0.0005952048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003864377,"about_ca_system_score_gemma":0.0006429437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005420377,"about_ca_topic_score_gemma":0.001480887,"domain_scores_codex":[0.9999305,0.00001081985,0.000003856176,0.00001461636,0.00001616717,0.00002406922],"domain_scores_gemma":[0.9999658,0.000002572145,0.000008196672,0.000001288651,0.00001011241,0.00001201997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001323076,0.0004806867,0.005841872,0.001496342,0.00008290742,0.0009874994,0.0005225902,0.001492205,0.8566083,0.01645045,0.003612264,0.1111018],"study_design_scores_gemma":[0.0002487945,0.00180022,0.2175357,0.0009534883,0.0003363182,0.002080199,0.001891416,0.004568467,0.6360092,0.01132937,0.1231487,0.0000981329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8090559,0.1162519,0.006034312,0.003377416,0.0004472825,0.0001284861,0.001177761,0.0001547808,0.06337199],"genre_scores_gemma":[0.886785,0.08177088,0.00339206,0.0003548223,0.000134934,0.00008350545,0.0008671561,0.00001765912,0.02659415],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002585631,"threshold_uncertainty_score":0.008649766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01205788917313042,"score_gpt":0.2485607763769141,"score_spread":0.2365028872037837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}