{"id":"W4240828665","doi":"10.1182/blood.v108.11.1868.1868","title":"In Vivo Control of Acute Lymphoblastic Leukemia by Immunostimulatory CpG Oligonucleotides.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital","funders":"","keywords":"Immunology; Medicine; CpG Oligodeoxynucleotide; Immune system; Transplantation; Severe combined immunodeficiency; Immunotherapy; Bone marrow; Cancer research; In vivo; Cancer; Leukemia; CpG site; Biology; Internal medicine; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002671688,0.0005136526,0.0001964419,0.000195354,0.00007709264,0.0001503718,0.0001013409,0.000296688,0.001242808],"category_scores_gemma":[0.0001053772,0.0001032278,0.0001801779,0.0001195267,0.0001744646,0.0001007294,0.0001063149,0.0005173311,0.0002603341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002103341,"about_ca_system_score_gemma":0.0001911347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003647502,"about_ca_topic_score_gemma":0.0005584235,"domain_scores_codex":[0.999854,0.00004104926,0.000009873605,0.00002727766,0.00003044976,0.00003744745],"domain_scores_gemma":[0.9999164,0.00002267677,0.00002219248,0.000008091096,0.00001004283,0.00002064414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002216112,0.00009041536,0.00003328645,0.00004425837,0.000002983916,0.000009148197,0.000007608231,0.00008947712,0.9983667,0.00004762356,0.0000265823,0.00106033],"study_design_scores_gemma":[0.00007425552,0.002646734,0.0005361424,0.000006871237,0.00001128138,0.00005676691,0.000007169829,0.0007564602,0.9947686,0.00002126775,0.001112905,0.000001665785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935458,0.00151693,0.00269505,0.00007697893,0.00008524269,0.0001079111,0.0003226018,0.00009384631,0.001555644],"genre_scores_gemma":[0.9921775,0.001103672,0.003347216,0.000076372,0.0000190104,0.0001540521,0.0005244382,0.00001761894,0.002580134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001242808,"threshold_uncertainty_score":0.004157662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002570247117955377,"score_gpt":0.1972781569963426,"score_spread":0.1947079098783872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}