{"id":"W4241473801","doi":"10.1002/ange.201510125","title":"A Catalytic DNA Activated by a Specific Strain of Bacterial Pathogen","year":2015,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; St. Joseph’s Healthcare Hamilton; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Deoxyribozyme; Strain (injury); Nucleic acid; DNA; Biology; Clostridium difficile; Microbiology; Bacteria; Pathogen; Chemistry; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001598593,0.0003982433,0.0001600831,0.0001919363,0.000125557,0.0002159389,0.0002515091,0.000356245,0.001802974],"category_scores_gemma":[0.0002455539,0.0001454527,0.0001708733,0.0001234449,0.000207589,0.0001133445,0.0001952758,0.0004056279,0.0004693743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002506091,"about_ca_system_score_gemma":0.000144066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00019988,"about_ca_topic_score_gemma":0.0002371651,"domain_scores_codex":[0.999806,0.00003268362,0.00001004606,0.00006955727,0.00004387157,0.0000379087],"domain_scores_gemma":[0.9998362,0.00004673926,0.0000501938,0.00002039855,0.00001514594,0.0000313222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001397013,0.000004597471,0.00008618043,0.00001632653,0.000001264682,0.00001475448,0.000004385553,0.0000245134,0.9992865,0.00004738805,0.00001180578,0.0004884142],"study_design_scores_gemma":[0.000002343544,0.00005228943,0.0003308752,0.000001573789,0.000002135614,0.0001148773,0.000004068193,0.0001822675,0.9984124,0.00001075185,0.0008849395,0.000001458226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794391,0.0007215269,0.01642102,0.0001293313,0.00006047133,0.00003813951,0.00015682,0.0001320567,0.002901582],"genre_scores_gemma":[0.9900194,0.0002371463,0.006516215,0.00006249501,0.000008400201,0.00002589436,0.0001933709,0.00001631705,0.002920636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001802974,"threshold_uncertainty_score":0.006031573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02040623737039635,"score_gpt":0.2291986101128246,"score_spread":0.2087923727424282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}