{"id":"W4241580772","doi":"10.25251/skin.4.supp.30","title":"Tapinarof Cream for the Treatment of Plaque Psoriasis: Efficacy and Safety by Baseline Disease Characteristics and Skin Type in a Phase 2b Randomized Study","year":2020,"lang":"en","type":"article","venue":"SKIN The Journal of Cutaneous Medicine","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; University of British Columbia","funders":"","keywords":"Plaque psoriasis; Medicine; Dermatology; Psoriasis; Baseline (sea); Phase (matter); Randomized controlled trial; Internal medicine; Biology; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002310486,0.002194904,0.004005601,0.0005245581,0.0004978307,0.001403444,0.001173862,0.001876034,0.008197984],"category_scores_gemma":[0.001955381,0.001059542,0.001925285,0.0006418451,0.001474375,0.001603176,0.0004805646,0.003677997,0.001100508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007732866,"about_ca_system_score_gemma":0.001272189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001037177,"about_ca_topic_score_gemma":0.001818922,"domain_scores_codex":[0.9990891,0.0004399926,0.00004181562,0.0001591532,0.0001036169,0.0001662808],"domain_scores_gemma":[0.9985043,0.000475627,0.0002710069,0.000157168,0.0001149641,0.000476956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9733729,0.0105588,0.0005203502,0.0003746012,0.0006480679,0.0000295523,0.00003967582,0.0002120238,0.003128002,0.0000682204,0.0004496947,0.01059818],"study_design_scores_gemma":[0.9161348,0.08006077,0.002343355,0.00002403195,0.0004072631,0.00003162709,0.00001760121,0.0002646409,0.0002698132,0.0001069231,0.0003236869,0.0000155425],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.98858,0.004363104,0.000618031,0.0003994662,0.000251483,0.003036853,0.001264594,0.00009847191,0.001387847],"genre_scores_gemma":[0.9845599,0.004291885,0.001668502,0.0008771955,0.0005668576,0.0037434,0.001522344,0.00005390971,0.002715933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008197984,"threshold_uncertainty_score":0.02742499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703836544243391,"score_gpt":0.2787548648414456,"score_spread":0.2617164993990116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}