{"id":"W4241792798","doi":"10.1002/ange.201606323","title":"A Convenient Late‐Stage Fluorination of Pyridylic C−H Bonds with <i>N</i>‐Fluorobenzenesulfonimide","year":2016,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Fluorine in Organic Chemistry","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Michael Smith Health Research BC","keywords":"Pyridine; Lipophilicity; Chemistry; Metabolic stability; Selectivity; Combinatorial chemistry; Fluorine; Halogenation; Stereochemistry; Organic chemistry; Catalysis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002511628,0.0003801725,0.0001636481,0.0001009195,0.0001695654,0.0001654245,0.0004029194,0.0003626449,0.001442727],"category_scores_gemma":[0.0002191807,0.0001508893,0.0001518847,0.00009825172,0.0002383046,0.0003067969,0.0002273906,0.0004293372,0.000335655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003263648,"about_ca_system_score_gemma":0.0003448428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009012758,"about_ca_topic_score_gemma":0.001376013,"domain_scores_codex":[0.9998626,0.00002086373,0.000009653874,0.0000385685,0.00002914314,0.00003909331],"domain_scores_gemma":[0.9999255,0.00001586672,0.0000239312,0.00001248773,0.000008588208,0.0000135875],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001012943,0.00002518365,0.00009155795,0.0001307972,0.000005410253,0.0001243725,0.00005541087,0.0001824926,0.9926153,0.001246918,0.0002927676,0.005128511],"study_design_scores_gemma":[0.00001211799,0.0002168212,0.0002818606,0.00000380443,0.000003547651,0.0001486279,0.000005677051,0.0003785575,0.9952925,0.00005938256,0.00358901,0.000008008537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8932321,0.004279176,0.07611815,0.0004221287,0.0001655629,0.0002514147,0.0009511343,0.0007121884,0.02386803],"genre_scores_gemma":[0.9891004,0.0007074796,0.007831239,0.00005181188,0.00001169055,0.00003500388,0.0001402054,0.00002262433,0.00209961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001442727,"threshold_uncertainty_score":0.004826427,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05444910211216989,"score_gpt":0.3500209118659449,"score_spread":0.295571809753775,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}