{"id":"W4242263566","doi":"10.32920/ryerson.14653002","title":"Regulation Of Endocytosis By Ultrasound And Microbubble Treatment: Potential For Controlled Cellular Delivery Of Drugs To Cancer Cells","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"Endocytosis; Endocytic cycle; Sonoporation; Clathrin; Cell biology; Intracellular; Exocytosis; Microbubbles; Receptor-mediated endocytosis; Chemistry; Biology; Cell; Medicine; Secretion; Biochemistry; Ultrasound","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004113476,0.0004547854,0.0003458444,0.0003368796,0.0002349377,0.0005940339,0.0003961337,0.0007090799,0.0007671099],"category_scores_gemma":[0.0003128916,0.0002325892,0.0004805805,0.000143869,0.0005069698,0.0005369413,0.0003788735,0.0008228336,0.0002835942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007131654,"about_ca_system_score_gemma":0.0004042492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004708237,"about_ca_topic_score_gemma":0.0004442116,"domain_scores_codex":[0.9998121,0.00003487894,0.000008661563,0.00003958473,0.00005675586,0.00004803068],"domain_scores_gemma":[0.9998839,0.0000379513,0.00002383088,0.00001045606,0.00001961878,0.00002417963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001073162,0.00002785485,0.0001953974,0.0001230768,0.000009739339,0.00007428242,0.0000364176,0.0001848761,0.9830862,0.002967067,0.0002562469,0.01293145],"study_design_scores_gemma":[0.00001834947,0.0002466906,0.0009669416,0.00001489559,0.00001872732,0.000256783,0.00001588917,0.001892559,0.9820355,0.0007473036,0.01377016,0.00001623158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7066835,0.1249846,0.1433788,0.008827659,0.0007739504,0.0005487503,0.000288503,0.0009752876,0.0135391],"genre_scores_gemma":[0.9219582,0.03294353,0.03204698,0.0009151337,0.0002494001,0.0002416218,0.000161664,0.0000739734,0.01140961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007671099,"threshold_uncertainty_score":0.005174458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006052134578753404,"score_gpt":0.2056882313101377,"score_spread":0.1996360967313843,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}