{"id":"W4242343919","doi":"10.1002/ange.202005624","title":"Ribbon of DNA Lattice on Gold Nanoparticles for Selective Drug Delivery to Cancer Cells","year":2020,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Science Foundation of Fujian Province; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Aptamer; Nanotechnology; DNA; Drug delivery; Colloidal gold; Nanomaterials; Fluorescence; Cancer cell; Drug; Nanoparticle; Ribbon; Biophysics; Chemistry; Targeted drug delivery; Materials science; Combinatorial chemistry; Cancer; Molecular biology; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001470928,0.0003043059,0.000172587,0.0002231364,0.0001290444,0.0002618883,0.0002978224,0.0003587866,0.0008274726],"category_scores_gemma":[0.0002082853,0.0002146627,0.0002330707,0.0001292789,0.0002275848,0.0002112411,0.000263552,0.0002670504,0.0005317572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004032346,"about_ca_system_score_gemma":0.0003197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000458633,"about_ca_topic_score_gemma":0.0007910354,"domain_scores_codex":[0.9998673,0.00002291755,0.000008379604,0.0000399357,0.00004069227,0.00002084374],"domain_scores_gemma":[0.9998735,0.00002746145,0.00003777985,0.0000156578,0.00001742346,0.000028104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004627558,0.00001500032,0.00004765482,0.00006824148,0.000005364415,0.00004769005,0.00001762237,0.0006287954,0.9954745,0.0003586246,0.00005557154,0.003234657],"study_design_scores_gemma":[0.00001338954,0.0001104644,0.0001506868,0.000003958718,0.000006177662,0.00005551652,0.000003900564,0.001612927,0.9951141,0.0000381434,0.002884049,0.000006630509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9377918,0.004449226,0.04434553,0.0003557024,0.0002260812,0.0001727012,0.0002183375,0.0008586079,0.01158197],"genre_scores_gemma":[0.9513328,0.001185403,0.04132718,0.0001251357,0.00002115068,0.0000698578,0.0001209904,0.00007104823,0.005746467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008274726,"threshold_uncertainty_score":0.002925754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.016112249007769,"score_gpt":0.2701994087247628,"score_spread":0.2540871597169939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}