{"id":"W4242502959","doi":"10.1002/ange.201912518","title":"Direct Catalytic Decarboxylative Amination of Aryl Acetic Acids","year":2019,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Amination; Decarboxylation; Nucleophile; Aryl; Electrophile; Organic chemistry; Isocyanate; Carboxylic acid; Oxidative decarboxylation; Catalysis; Combinatorial chemistry; Alkyl; Amine gas treating","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002320706,0.0001859377,0.0003037793,0.00008078218,0.0000329182,0.00001640187,0.0001856701,0.0001413925,0.003147692],"category_scores_gemma":[0.0003512273,0.0001899289,0.0001233274,0.0003195432,0.00008490188,0.000143231,0.00008074335,0.0001215129,0.0001189214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001610862,"about_ca_system_score_gemma":0.00008531503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003319824,"about_ca_topic_score_gemma":0.000005015164,"domain_scores_codex":[0.9987612,0.000007345545,0.0003241457,0.0003441072,0.0003590714,0.0002041019],"domain_scores_gemma":[0.9986982,0.0003296762,0.0002091125,0.0004919898,0.000196108,0.00007486461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003764869,0.0000626914,0.01037409,0.000251105,0.00007773285,0.000001777454,0.0004059419,0.00004687538,0.9872149,0.000232134,0.0006689728,0.0006261132],"study_design_scores_gemma":[0.0006271044,0.00001554321,0.001812038,0.00007517108,0.00006956476,0.000007444501,0.0001604711,0.0001255208,0.9917516,0.000229438,0.004925346,0.0002008257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7724562,0.0003472808,0.0005485385,0.0000978575,0.0002329782,0.0001412734,0.0000699677,0.0001172102,0.2259887],"genre_scores_gemma":[0.9825284,0.00002706069,0.0005324481,0.00004670677,0.0001184675,0.00002025423,0.0003651986,0.00003478282,0.01632664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2100723,"threshold_uncertainty_score":0.9977636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01741520557003491,"score_gpt":0.2691391722048554,"score_spread":0.2517239666348206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}