{"id":"W4242502959","doi":"10.1002/ange.201912518","title":"Direct Catalytic Decarboxylative Amination of Aryl Acetic Acids","year":2019,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Amination; Decarboxylation; Nucleophile; Aryl; Electrophile; Organic chemistry; Isocyanate; Carboxylic acid; Oxidative decarboxylation; Catalysis; Combinatorial chemistry; Alkyl; Amine gas treating","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002378717,0.0005525381,0.000236577,0.0002926429,0.0002092315,0.000186472,0.0003915747,0.0002965669,0.001768119],"category_scores_gemma":[0.0002389792,0.0001863659,0.0001901943,0.000190199,0.0002661826,0.0003296184,0.0005507407,0.0006450661,0.000781845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002631081,"about_ca_system_score_gemma":0.0002707604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003457344,"about_ca_topic_score_gemma":0.0009783366,"domain_scores_codex":[0.9997782,0.00002717008,0.00001680138,0.00005169018,0.00005149755,0.00007462612],"domain_scores_gemma":[0.9999185,0.00001213155,0.0000249617,0.00001304614,0.00001281358,0.0000186995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008935594,0.00005099453,0.0001816471,0.0002293596,0.00001927172,0.0002427539,0.00009834048,0.0002225638,0.9866648,0.001987644,0.0003710683,0.009842203],"study_design_scores_gemma":[0.00001678016,0.0001622516,0.0003381942,0.000006103732,0.000007303921,0.0001704541,0.00001245513,0.0004304266,0.9936201,0.0001010999,0.005126745,0.000008010771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.908367,0.003771609,0.04850212,0.0003506571,0.0003324785,0.0002357846,0.0005065826,0.0003117636,0.03762206],"genre_scores_gemma":[0.987818,0.00139339,0.006485961,0.00005577345,0.00002701239,0.00003174123,0.0001361096,0.00002777174,0.004024207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001768119,"threshold_uncertainty_score":0.005914927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01741520557003491,"score_gpt":0.2691391722048554,"score_spread":0.2517239666348206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}