{"id":"W4242746349","doi":"10.1017/cjn.2019.89","title":"A.07 Efficacy, safety, and tolerability of ubrogepant for the acute treatment of migraine: a single-attack phase 3 study, ACHIEVE I","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","topic":"Migraine and Headache Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Tolerability; Somnolence; Migraine; Placebo; Medicine; Adverse effect; Nausea; Population; Clinical endpoint; Internal medicine; Randomized controlled trial; Anesthesia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001323636,0.0008720697,0.001629139,0.0003552496,0.0004354068,0.0007759036,0.0006634602,0.001024061,0.008913549],"category_scores_gemma":[0.0009735702,0.0004692562,0.001628281,0.000265208,0.0006500891,0.0006217106,0.0003017733,0.002190476,0.001656871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003576523,"about_ca_system_score_gemma":0.001135511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005266575,"about_ca_topic_score_gemma":0.001165252,"domain_scores_codex":[0.9996428,0.0001613648,0.00002057123,0.00005573961,0.00004990214,0.00006944393],"domain_scores_gemma":[0.9992566,0.000125197,0.0002298856,0.00008637737,0.00005959643,0.0002424145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8728082,0.02526896,0.002807259,0.001328003,0.00130271,0.0001642431,0.0001633032,0.0006307408,0.03006234,0.0002860217,0.005186307,0.059992],"study_design_scores_gemma":[0.7410573,0.2435277,0.008990352,0.00005534932,0.0006460087,0.0002160273,0.0000291858,0.0006490017,0.002330426,0.0002660506,0.002211198,0.00002138554],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982692,0.002646548,0.00147044,0.0005822345,0.0001366842,0.004847665,0.00335964,0.0003836186,0.003881158],"genre_scores_gemma":[0.975806,0.002209509,0.004535615,0.001905141,0.0003740008,0.00635286,0.003616592,0.0001104561,0.005089775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008913549,"threshold_uncertainty_score":0.02981877,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07182122964673743,"score_gpt":0.3452036557958231,"score_spread":0.2733824261490856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}