{"id":"W4243058622","doi":"10.1182/blood.v124.21.3580.3580","title":"IDH2 R172 Mutations Define a Unique Subgroup of Patients in Angioimmunoblastic T-Cell Lymphoma","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Angioimmunoblastic T-cell lymphoma; Epigenetics; Biology; IDH2; Cancer research; DNA methylation; Molecular biology; Lymphoma; Mutation; Genetics; T cell; Immunology; Gene; Gene expression; IDH1","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007151904,0.00008833555,0.0001002616,0.00006368803,0.00002030464,0.00000470629,0.00008188425,0.0001138588,0.000006259888],"category_scores_gemma":[0.00005641103,0.00009606156,0.00005083712,0.0001368569,0.00003431519,0.000002486153,0.00003635805,0.00002663418,0.000005160479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001347809,"about_ca_system_score_gemma":0.00004970396,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006381342,"about_ca_topic_score_gemma":0.0001468414,"domain_scores_codex":[0.9993741,0.0000467894,0.0002024644,0.0001712128,0.00007908995,0.0001263805],"domain_scores_gemma":[0.9995823,0.00001408052,0.00009215238,0.0002128555,0.00007114271,0.00002750469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001193974,0.001925941,0.0807931,0.00007030895,0.00007085755,8.286135e-7,0.0001725331,0.001128167,0.9092578,0.0001923875,0.0001530636,0.006115624],"study_design_scores_gemma":[0.006121798,0.0004782294,0.3253991,0.00003170117,0.0000608775,0.000002928831,0.00001319828,0.0002691133,0.6658823,0.0001937047,0.001358869,0.0001881891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980707,0.0002514561,0.0008897302,0.00001150689,0.00005874239,0.0001335356,0.00001515401,0.000006754177,0.0005624261],"genre_scores_gemma":[0.999124,0.00003218366,0.0003816723,0.00001706952,0.00003817709,0.00001625391,0.0003018565,0.00001607781,0.00007270454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.244606,"threshold_uncertainty_score":0.3917277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002684100064832114,"score_gpt":0.1865197086800092,"score_spread":0.1838356086151771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}