{"id":"W4243070409","doi":"10.1016/b978-0-12-812215-0.00029-7","title":"Stem Cell Epigenetics and Human Disease","year":2018,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Epigenetics; Disease; Human disease; Biology; Computational biology; Neuroscience; Medicine; Genetics; Pathology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002092654,0.0005217927,0.0002928757,0.0007027338,0.0002681173,0.001347205,0.0004101189,0.0008131926,0.06398883],"category_scores_gemma":[0.0002132715,0.0001400823,0.0001578417,0.0007201717,0.0005123971,0.001145382,0.0007820238,0.001013492,0.02261371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004610337,"about_ca_system_score_gemma":0.0004458209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007129955,"about_ca_topic_score_gemma":0.001570051,"domain_scores_codex":[0.9999285,0.000008104755,0.000003378126,0.00001346428,0.00003875839,0.000007895624],"domain_scores_gemma":[0.9999598,0.00001487515,0.000003438973,0.000004359321,0.000009101901,0.000008432441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003437098,0.00003559899,0.0001518962,0.0002850543,0.000007514443,0.0002012467,0.0001288625,0.0003043155,0.00832589,0.06696484,0.1318194,0.7917411],"study_design_scores_gemma":[0.000003411119,0.000008232162,0.0001804517,0.00009509147,0.000002603024,0.0002298681,0.00003280584,0.0000697271,0.0007779384,0.01508338,0.9835134,0.000003000414],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.003612937,0.2503479,0.01079794,0.00862634,0.005215286,0.00004238637,0.0005348356,0.0004765949,0.7203459],"genre_scores_gemma":[0.01266607,0.09499788,0.004229105,0.0015393,0.001470865,0.00004658931,0.0003174934,0.00009914012,0.8846336],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.06398883,"threshold_uncertainty_score":0.214064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01334789949840805,"score_gpt":0.2417068313740271,"score_spread":0.2283589318756191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}