{"id":"W4243088410","doi":"10.1002/ange.201808509","title":"Rhodium‐Catalyzed Enantioselective Defluorinative α‐Arylation of Secondary Amides","year":2018,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Advanced Synthetic Organic Chemistry","field":"Chemistry","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Stereocenter; Rhodium; Enantioselective synthesis; Chemistry; Catalysis; Olefin fiber; Reactivity (psychology); Diene; Combinatorial chemistry; Organic chemistry; Acceptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001152096,0.0002510327,0.0003267092,0.00004208239,0.0001060794,0.00001330319,0.0002684444,0.000188422,0.003732482],"category_scores_gemma":[0.0003429841,0.0002528638,0.0001133311,0.0002436169,0.0004400827,0.0001880444,0.0001153412,0.0002378172,0.00005367554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001605415,"about_ca_system_score_gemma":0.0001319172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002550991,"about_ca_topic_score_gemma":0.00001150022,"domain_scores_codex":[0.9986147,0.000009063609,0.0003662101,0.0004341019,0.0002534466,0.0003225214],"domain_scores_gemma":[0.9986538,0.0001807684,0.0002865431,0.0004751921,0.000309398,0.00009432382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006867729,0.00007346506,0.0004348095,0.0001372116,0.00007711154,0.000003732012,0.0007178867,2.58008e-7,0.9949009,0.00009047019,0.0004034757,0.003092011],"study_design_scores_gemma":[0.0007097164,0.00002141392,0.000201289,0.0000860559,0.0000457559,0.00002055005,0.0004521228,0.000006661793,0.9938054,0.00205238,0.002331901,0.0002667296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8377394,0.0002404397,0.0004100228,0.00007722802,0.00008139178,0.00006662813,0.00008797969,0.0001344888,0.1611624],"genre_scores_gemma":[0.9960251,0.00003461839,0.001339685,0.00002748456,0.0003807176,0.00001634957,0.00008851051,0.0000462666,0.002041285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1591211,"threshold_uncertainty_score":0.9999924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01123237682797341,"score_gpt":0.2500044425558601,"score_spread":0.2387720657278867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}