{"id":"W4243207305","doi":"10.21203/rs.2.276/v2","title":"Tranexamic acid for acute gastrointestinal bleeding (The HALT-IT trial): Statistical analysis plan for an international, randomised, double blind, placebo-controlled trial","year":2019,"lang":"en","type":"preprint","venue":"Research Square","topic":"Gastrointestinal Bleeding Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Health Technology Assessment Programme; National Institute for Health and Care Research","keywords":"Tranexamic acid; Medicine; Placebo; Upper gastrointestinal bleeding; Randomized controlled trial; Gastrointestinal bleeding; Surgery; Internal medicine; Anesthesia; Endoscopy; Blood loss","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02599838,0.003477955,0.0073601,0.00110985,0.0007534422,0.002716702,0.001312364,0.002933264,0.02349742],"category_scores_gemma":[0.0348334,0.001390672,0.009164369,0.001590599,0.00196093,0.00211715,0.001571749,0.005271408,0.003268452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001547775,"about_ca_system_score_gemma":0.003673565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001062604,"about_ca_topic_score_gemma":0.00134514,"domain_scores_codex":[0.975611,0.01927194,0.001543017,0.001092338,0.00125366,0.001228147],"domain_scores_gemma":[0.9899769,0.004773741,0.002186642,0.001473429,0.0008599325,0.0007292238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.9720081,0.0004607246,0.0005059261,0.00323008,0.0041926,0.00003214029,0.00005122923,0.0008073186,0.0004769573,0.001638267,0.003568612,0.01302809],"study_design_scores_gemma":[0.9723496,0.01010343,0.001389915,0.0005845277,0.006376264,0.00002668718,0.00003831715,0.001712942,0.000448236,0.002349956,0.004568106,0.00005197786],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.2071896,0.02631459,0.08263751,0.008979901,0.007342733,0.5905085,0.04946049,0.002465884,0.02510085],"genre_scores_gemma":[0.2251916,0.005635343,0.0762925,0.003300078,0.001258412,0.6670224,0.009441492,0.0004233076,0.01143482],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02599838,"threshold_uncertainty_score":0.1374943,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1632865670567673,"score_gpt":0.4612887355283857,"score_spread":0.2980021684716184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}