{"id":"W4243314230","doi":"10.32920/ryerson.14651847.v1","title":"Understanding Pikfyve Control Of Lysome Dynamics","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University; University of Waterloo","funders":"","keywords":"Lysosome; Cell biology; Endosome; Autophagy; Lipid bilayer fusion; Biology; Endocytosis; Phagosome; Chemistry; Biochemistry; Phagocytosis; Membrane; Cell; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002291899,0.0003415673,0.0003209129,0.0002303213,0.0001802346,0.0009156164,0.0005750618,0.0006511174,0.0007121161],"category_scores_gemma":[0.0001515123,0.000231922,0.0002774098,0.0001246704,0.0004608356,0.001191222,0.0004434416,0.001022848,0.0003942479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008726232,"about_ca_system_score_gemma":0.0003493284,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008185558,"about_ca_topic_score_gemma":0.000809022,"domain_scores_codex":[0.9998606,0.000009133943,0.00001201859,0.00004057315,0.00003935396,0.00003821219],"domain_scores_gemma":[0.9998786,0.00001345883,0.00004544891,0.000008350215,0.00001850792,0.00003569592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001567503,0.00001876208,0.000896011,0.0001424582,0.00001248377,0.0002062821,0.00005379517,0.0006846129,0.9858205,0.003893613,0.0002773942,0.007837318],"study_design_scores_gemma":[0.00004709868,0.0002321451,0.02023081,0.00006200145,0.00004925648,0.001050172,0.0002614098,0.02371047,0.910091,0.005753526,0.03846388,0.00004824117],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9152832,0.03303929,0.03659076,0.002810793,0.0002459246,0.00005494026,0.0007609648,0.0006766299,0.01053755],"genre_scores_gemma":[0.9763805,0.01497034,0.004072067,0.0003151791,0.0000671858,0.00003698052,0.0003158585,0.00005403414,0.003787881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009156164,"threshold_uncertainty_score":0.006331384,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03048038873667529,"score_gpt":0.2313719038200132,"score_spread":0.2008915150833379,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}