{"id":"W4243455690","doi":"10.2174/2210304x11101020118","title":"Delivery Systems for Applications in siRNA Technology","year":2011,"lang":"en","type":"article","venue":"Drug Delivery Letters","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Small interfering RNA; RNA interference; Nanocarriers; RNA; Trans-acting siRNA; Viral vector; Gene silencing; Computational biology; Biology; Cell biology; Gene; Genetics; Pharmacology; Drug","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000633663,0.0007588692,0.0007117928,0.0007880792,0.0004686574,0.001038248,0.00052578,0.001451226,0.01010632],"category_scores_gemma":[0.0004727494,0.0003405991,0.0005353806,0.0004976793,0.0003158109,0.001120057,0.0006708193,0.001074141,0.009124435],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006668484,"about_ca_system_score_gemma":0.0005165536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003256556,"about_ca_topic_score_gemma":0.0003791745,"domain_scores_codex":[0.9995723,0.00006892619,0.00004124974,0.00008278387,0.0001952943,0.00003940284],"domain_scores_gemma":[0.9998376,0.00004472044,0.00002718834,0.00001652167,0.00005514307,0.00001870417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008872854,0.00005937566,0.00007257672,0.00158067,0.00002001321,0.0003994195,0.0001403397,0.0003633543,0.857273,0.01418032,0.005590471,0.1202318],"study_design_scores_gemma":[0.0000445374,0.0004868906,0.0002691072,0.0001806242,0.00005915701,0.00124571,0.00003971231,0.001392281,0.4428379,0.002960883,0.5504442,0.00003889362],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.06211988,0.2862023,0.5190499,0.005509109,0.0051275,0.002598964,0.00162485,0.004341228,0.1134263],"genre_scores_gemma":[0.232868,0.1858575,0.3969521,0.003997551,0.001166845,0.002784359,0.002511424,0.0007484543,0.1731138],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.01010632,"threshold_uncertainty_score":0.03380901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01375422058433917,"score_gpt":0.2193686875187707,"score_spread":0.2056144669344315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}