{"id":"W4243984006","doi":"10.32920/ryerson.14651550.v1","title":"Treatment of pancreatic cancer cells in vitro using ultrasound, microbubbles, and gemicitabine","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Ultrasound and Hyperthermia Applications","field":"Engineering","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"Sonoporation; Microbubbles; Gemcitabine; Programmed cell death; Pancreatic cancer; Cytotoxicity; In vitro; Cancer research; Biophysics; Chemistry; Viability assay; Cancer cell; Cytotoxic T cell; Apoptosis; Cell; Cell biology; Ultrasound; Chemotherapy; Cancer; Medicine; Biology; Biochemistry; Internal medicine; Radiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003739582,0.0003517136,0.0005380274,0.0002087433,0.0002236557,0.0004585705,0.0002086361,0.0003404078,0.00102998],"category_scores_gemma":[0.000226951,0.0002347599,0.000426677,0.0003511735,0.0002439224,0.0002526071,0.0002337421,0.0005691536,0.0003941593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002913717,"about_ca_system_score_gemma":0.0003308008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002538818,"about_ca_topic_score_gemma":0.002505381,"domain_scores_codex":[0.9996436,0.0001217529,0.00004727397,0.00005800972,0.00006195466,0.00006734388],"domain_scores_gemma":[0.9998525,0.00008530157,0.00001161997,0.00002251813,0.00001425612,0.00001372539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004115124,0.00009119964,0.0003594794,0.0002333422,0.00002433906,0.0001387952,0.0002152821,0.0006236931,0.9932634,0.0001846781,0.0001399122,0.004314283],"study_design_scores_gemma":[0.00001874805,0.0005978236,0.001028274,0.000008085391,0.00002153515,0.000103947,0.00005814573,0.0008943542,0.9942846,0.0000376871,0.002942655,0.000004142255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9732471,0.008859194,0.009273857,0.0003386048,0.0001363267,0.0001362015,0.0006809177,0.0001315689,0.007196257],"genre_scores_gemma":[0.980343,0.004924338,0.008903751,0.0001441029,0.00002929973,0.00009111573,0.001148968,0.00003770087,0.004377728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002538818,"threshold_uncertainty_score":0.005048037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01567317233406785,"score_gpt":0.2357830505750258,"score_spread":0.2201098782409579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}