{"id":"W4244013818","doi":"10.1002/0470028637.met042","title":"Calpain","year":2004,"lang":"en","type":"other","venue":"Handbook of Metalloproteins","topic":"Calpain Protease Function and Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Calpain; Proteases; Protease; Papain; Active site; Gene isoform; Chemistry; Enzyme; Cysteine protease; Biochemistry; Catalytic triad; Intracellular; Binding site; Cell biology; Biophysics; Stereochemistry; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002094824,0.001159044,0.0003639613,0.001108553,0.0003928504,0.001257239,0.0007154847,0.0006900629,0.07562584],"category_scores_gemma":[0.0002536335,0.0001824388,0.0002960821,0.0006837561,0.0001951584,0.000647473,0.0006804363,0.0009038537,0.04184969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000593597,"about_ca_system_score_gemma":0.0003211759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006613485,"about_ca_topic_score_gemma":0.0008802786,"domain_scores_codex":[0.9998205,0.000008308297,0.00001046984,0.00005092634,0.00008137742,0.00002832473],"domain_scores_gemma":[0.9998857,0.000008294746,0.00001110972,0.00001460263,0.00004642553,0.00003400573],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004175572,0.0001833023,0.000697534,0.001370655,0.00004439687,0.0009168597,0.00007845282,0.0003442044,0.3414241,0.01246832,0.1028259,0.5392288],"study_design_scores_gemma":[0.00003368808,0.00008430937,0.001614852,0.00007135338,0.00001791617,0.001342898,0.00002298638,0.000260572,0.06208527,0.001945548,0.9325125,0.000008112093],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.03962484,0.1525758,0.02933799,0.003838092,0.008166078,0.0004568114,0.010121,0.004079818,0.7517996],"genre_scores_gemma":[0.08453428,0.03842314,0.01187435,0.001047926,0.001035888,0.0001263359,0.01209713,0.0002197795,0.8506411],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.07562584,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005674040733925804,"score_gpt":0.2146394745324861,"score_spread":0.2089654337985603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}